Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12442424 | 0.81 | P2RX7 (0.42) | P2RX7HDAC1MAPTKDM4EPTGS2 | |
| SCHEMBL11691729 | 0.78 | P2RX7 (0.42) | P2RX7MAPTATMKDM4EPTGS2 | |
| SCHEMBL11696173 | 0.78 | P2RX7 (0.42) | P2RX7HIF1AMAPTKDM4ENPSR1 | |
| SCHEMBL23367193 | 0.78 | KIF11 (0.42) | P2RX7 | |
| SCHEMBL9814514 | 0.78 | P2RX7 (0.62) | P2RX7HDAC1MAPTATMKDM4E | |
| SCHEMBL23384990 | 0.75 | MAPT (0.38) | HIF1AXDHTDP1MAPTATM | |
| SCHEMBL11766757 | 0.74 | HTT (0.47) | P2RX7HIF1AMAPTNPBWR1MCHR1 | |
| SCHEMBL11695053 | 0.74 | P2RX7 (0.46) | P2RX7XDHTDP1MAPTKDM4E | |
| SCHEMBL9213953 | 0.74 | GABRB3 (0.43) | — | |
| SCHEMBL15578585 | 0.73 | SRD5A2 (0.41) | HIF1AHDAC1MAPTATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |