Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23367252 | 0.78 | P2RX7 (0.40) | P2RX7 | |
| SCHEMBL23354805 | 0.77 | ASPH (0.39) | KIF11CYP11B2CYP11B1GRM2KCNQ3 | |
| SCHEMBL12442424 | 0.76 | P2RX7 (0.42) | P2RX7 | |
| SCHEMBL23354747 | 0.70 | ALDH1A1 (0.39) | CYP11B2CYP11B1 | |
| SCHEMBL11691729 | 0.69 | P2RX7 (0.42) | P2RX7 | |
| SCHEMBL11696173 | 0.69 | P2RX7 (0.42) | P2RX7 | |
| SCHEMBL9814514 | 0.69 | P2RX7 (0.62) | P2RX7 | |
| SCHEMBL9211834 | 0.68 | ERN1 (0.34) | — | |
| SCHEMBL31568323 | 0.68 | L3MBTL1 (0.35) | P2RX7 | |
| SCHEMBL23367388 | 0.68 | P2RX7 (0.42) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021094434-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-20 | — | — | WO | disclosed |
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |