Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.42 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846221 | 0.86 | CYP1A2 (0.49) | POLBALDH1A1KHKPGK1CYP1A2 | |
| SCHEMBL566209 | 0.76 | KHK (0.57) | POLBALDH1A1KHKPGK1CYP1A2 | |
| SCHEMBL6955377 | 0.75 | CYP1A2 (0.51) | POLBALDH1A1KHKPGK1CYP1A2 | |
| SCHEMBL6627580 | 0.74 | ALDH1A1 (0.40) | POLBALDH1A1PGK1CTSKCTSS | |
| SCHEMBL6184247 | 0.73 | MBOAT4 (0.45) | POLBALDH1A1PGK1CYP1A2CYP2C9 | |
| SCHEMBL13040092 | 0.72 | KEAP1 (0.40) | CYP1A2PKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14642140 | 0.71 | PGK1 (0.45) | ALDH1A1PGK1CYP1A2KDM4EGAA | |
| SCHEMBL23860788 | 0.71 | MAPK1 (0.41) | ALDH1A1KHKSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL20302559 | 0.71 | ALDH1A1 (0.58) | POLBALDH1A1KHKPGK1CYP1A2 | |
| SCHEMBL33526375 | 0.71 | NPSR1 (0.59) | POLBALDH1A1KHKPGK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822270-A1 | NOVEL HETEROCYCLE DERIVATIVE | JW Pharmaceutical Corporation (KR) | 2021-05-19 | — | — | EP | disclosed |