SCHEMBL233708

SCHEMBL233708

CCN[Si](NCC)(NCC)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.39
TP53 P04637 1/20 0.38
GAA P10253 3/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 2/20 0.35
SIGMAR1 Q99720 1/20 0.35
ALDH1A1 P00352 1/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
HTT P42858 1/20 0.34
LMNA P02545 1/20 0.33
MAPT P10636 2/20 0.32
CYP3A4 P08684 1/20 0.32
PSIP1 O75475 1/20 0.32
TSHR P16473 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
ELANE P08246 1/20 0.32
ALPL P05186 1/20 0.31
ALOX12 P18054 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2100303 0.88 KCNN4 (0.35) KCNN4TP53GAAKDM4EHPGD
SCHEMBL9651955 0.80 MAPT (0.42) GAAKDM4EHPGDSIGMAR1ALDH1A1
SCHEMBL2268924 0.79 KCNN4 (0.39) KCNN4TP53GAAKDM4EHPGD
SCHEMBL2102177 0.79 KCNN4 (0.39) KCNN4TP53GAAKDM4EHPGD
SCHEMBL10791919 0.78 SIGMAR1 (0.47) HPGDSIGMAR1ALDH1A1HTTMAPT
SCHEMBL234050 0.77 ESR1 (0.38) KCNN4TP53GAAKDM4EHPGD
SCHEMBL2273250 0.77 ESR1 (0.38) KCNN4TP53GAAKDM4EHPGD
SCHEMBL9418728 0.77 ALDH1A1 (0.38) HPGDALDH1A1ESR1LMNAMAPT
SCHEMBL10709532 0.77 NAAA (0.46) SIGMAR1ALDH1A1HTTMAPT
SCHEMBL2099500 0.75 KCNN4 (0.37) KCNN4TP53GAAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8648001-B2 Aminosilane compounds, catalyst components and catalysts for olefin polymerization, and process for production of olefin polymers with the same TOHO TITANIUM CO., LTD. (JP) 2014-02-11 US disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20120053310-A1 Aminosilane Compounds, Catalyst Components and Catalysts for Olefin Polymerization, and Process for Production of Olefin Polymers with the Same TOHO TITANIUM CO., LTD. (JP) 2012-03-01 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed
US-20100190942-A1 AMINOSILANE COMPOUNDS, CATALYST COMPONENTS AND CATALYSTS FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS WITH THE SAME TOHO CATALYST CO., LTD. (JP) 2010-07-29 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed
EP-1908767-A1 AMINOSILANE COMPOUNDS, CATALYST COMPONENTS AND CATALYSTS FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS WITH THE SAME Toho Catalyst Co., Ltd. (JP) 2008-04-09 EP disclosed
EP-0387157-B1 Aqueous silicone dispersion which contains an aminosilane and/or an amidosilane, is curable into an elastomer by the elimination of water RHONE POULENC CHIMIE (FR) 1994-07-27 EP disclosed
US-5140061-A Storage stability; adhesion to substrates, e.g.glass, concrete and metals; coatings for use with drugs and agriculture; seals RHONE-POULENC CHIMIE (FR) 1992-08-18 US disclosed
EP-0387157-A1 Aqueous silicone dispersion which contains an aminosilane and/or an amidosilane, is curable into an elastomer by the elimination of water RHONE-POULENC CHIMIE (FR) 1990-09-12 EP disclosed