Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL233708 | 0.77 | KCNN4 (0.39) | ALDH1A1MAPTESR1HPGDLMNA | |
| SCHEMBL9651955 | 0.68 | MAPT (0.42) | ALDH1A1MAPTACP1HPGD | |
| SCHEMBL10791919 | 0.67 | SIGMAR1 (0.47) | ALDH1A1MAPTHPGD | |
| SCHEMBL2100303 | 0.67 | KCNN4 (0.35) | ALDH1A1MAPTESR1TAAR1HPGD | |
| SCHEMBL5228652 | 0.67 | APAF1 (0.63) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL26217022 | 0.67 | APAF1 (0.63) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL5227140 | 0.67 | APAF1 (0.63) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL2100879 | 0.66 | TSHR (0.41) | ALDH1A1MAPTESR1TAAR1HPGD | |
| SCHEMBL10709532 | 0.65 | NAAA (0.46) | ALDH1A1MAPT | |
| SCHEMBL182877 | 0.65 | MAPT (0.52) | ALDH1A1MEN1MAPTKMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387157-B1 | Aqueous silicone dispersion which contains an aminosilane and/or an amidosilane, is curable into an elastomer by the elimination of water | RHONE POULENC CHIMIE (FR) | 1994-07-27 | — | — | EP | disclosed |
| US-5140061-A | Storage stability; adhesion to substrates, e.g.glass, concrete and metals; coatings for use with drugs and agriculture; seals | RHONE-POULENC CHIMIE (FR) | 1992-08-18 | — | — | US | disclosed |
| EP-0387157-A1 | Aqueous silicone dispersion which contains an aminosilane and/or an amidosilane, is curable into an elastomer by the elimination of water | RHONE-POULENC CHIMIE (FR) | 1990-09-12 | — | — | EP | disclosed |