Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 7/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27177131 | 0.77 | CCNA2 (0.34) | CCNA2CDK2CCNA1CCR4POLB | |
| SCHEMBL12892475 | 0.74 | CHRNB2 (0.33) | TDP2NSD2 | |
| SCHEMBL19407671 | 0.73 | CRHBP (0.59) | MERTKTDP2NSD2ALDH1A1GAA | |
| SCHEMBL10071721 | 0.73 | CYP3A4 (0.32) | TDP2NSD2CRHBPCRHR2 | |
| SCHEMBL30503540 | 0.73 | CRHBP (0.59) | MERTKTDP2NSD2ALDH1A1GAA | |
| SCHEMBL15195554 | 0.71 | CRHBP (0.42) | MERTKTDP2NSD2ALDH1A1GAA | |
| SCHEMBL19237079 | 0.71 | PDCD1LG2 (0.44) | MERTKTDP2NSD2ALDH1A1GAA | |
| SCHEMBL29361411 | 0.70 | NNMT (0.49) | MERTKALDH1A1HPGDSMN1; SMN2CDK2 | |
| SCHEMBL2527039 | 0.70 | NNMT (0.49) | MERTKALDH1A1HPGDSMN1; SMN2CDK2 | |
| SCHEMBL16234979 | 0.69 | CRHBP (0.41) | MERTKTDP2NSD2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210147453-A1 | DIMETHYLPHOSPHINE OXIDE COMPOUND | Guizhou Inochini Technology Co., Ltd (CN) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147453-A1 | DIMETHYLPHOSPHINE OXIDE COMPOUND | LRRK2, PDPK1, PARK7 | MERTK 1344/4885TDP2 459/4885NSD2 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.