Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17695458 | 0.87 | ABCB1 (0.61) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL10082964 | 0.85 | ABCB1 (0.59) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL19269178 | 0.85 | ABCB1 (0.59) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14176752 | 0.83 | ABCB1 (0.62) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL458205 | 0.83 | ABCB1 (0.77) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL12964718 | 0.83 | ABCB1 (0.56) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL23182124 | 0.82 | ABCB1 (0.59) | ABCB1USP2ATMCFTRPAX8 | |
| Hydrochloric Acid SCHEMBL5606345 | 0.82 | USP2 (0.76) | ABCB1USP2ATMCFTRPAX8 | |
| Hydrochloric Acid SCHEMBL29376502 | 0.82 | USP2 (0.76) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL18626401 | 0.82 | ABCB1 (0.55) | ABCB1USP2ATMCFTRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030864-B2 | Small molecule anticancer agents, combinations and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-07-09 | — | — | US | disclosed |
| US-20210147379-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS, COMBINATIONS AND USES THEREOF | University of Florda Research Foundation,Incorporated (US) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147379-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS, COMBINATIONS AND USES THEREOF | MKI67, TP53, PLK1 | ABCB1 853/4885USP2 2726/4885ATM 611/4885 |
| US-12030864-B2 | Small molecule anticancer agents, combinations and uses thereof | MKI67, TP53, PCNA | ABCB1 649/4885USP2 3220/4885ATM 730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.