Bisoprolol

Bisoprolol

SCHEMBL233810

CC(C)NC[C@@H](O)COc1ccc(COCCOC(C)C)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1

The experimentally established mechanism targets of Bisoprolol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 known ✓ P08588 5/20 1.00
ADRB2 P07550 4/20 1.00
ADRB3 P13945 2/20 1.00
LMNA P02545 3/20 0.83
NFKB1 P19838 2/20 0.83
MEN1 O00255 1/20 0.83
THRB P10828 1/20 0.83
ALOX12 P18054 1/20 0.83
APEX1 P27695 1/20 0.83
MAPK1 P28482 1/20 0.83
KMT2A Q03164 1/20 0.83
PTGS1 P23219 1/20 0.63
SLC6A2 P23975 1/20 0.63
CYP2D6 P10635 3/20 0.62
ADRA1A P35348 2/20 0.62
NR3C1 P04150 1/20 0.62
CYP2J2 P51589 1/20 0.62
PDE4D Q08499 1/20 0.62
MAPT P10636 1/20 0.60
TDP1 Q9NUW8 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bisoprolol SCHEMBL20961 1.00 ADRB1 (1.00) ADRB1ADRB2ADRB3LMNANFKB1
Bisoprolol SCHEMBL6510329 1.00 ADRB1 (1.00) ADRB1ADRB2ADRB3LMNANFKB1
Bisoprolol SCHEMBL20960 1.00 ADRB1 (1.00) ADRB1ADRB2ADRB3LMNANFKB1
Bisoprolol SCHEMBL16821829 0.99 ADRB1 (0.98) ADRB1ADRB2ADRB3LMNANFKB1
Bisoprolol SCHEMBL16821831 0.99 ADRB1 (0.98) ADRB1ADRB2ADRB3LMNANFKB1
Bisoprolol SCHEMBL4269272 0.99 ADRB1 (0.98) ADRB1ADRB2ADRB3LMNANFKB1
Bisoprolol SCHEMBL3137111 0.99 ADRB2 (0.98) ADRB1ADRB2ADRB3LMNANFKB1
Bisoprolol SCHEMBL3137123 0.99 ADRB2 (0.98) ADRB1ADRB2ADRB3LMNANFKB1
Bisoprolol SCHEMBL14343724 0.94 ADRB2 (0.89) ADRB1ADRB2ADRB3LMNANFKB1
Bisoprolol SCHEMBL28880254 0.94 ADRB2 (0.89) ADRB1ADRB2ADRB3LMNANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2522 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4691556-A2 HUMANIZED ANTI-ACTH ANTIBODIES AND USE THEREOF H. Lundbeck A/S (DK) 2026-02-11 EP claimed
EP-4637708-A2 SEMIFLUORINATED ALKANE COMPOSITIONS COMPRISING HYOSCYAMINE Novaliq GmbH (DE) 2025-10-29 EP claimed
US-20250264469-A1 METHODS FOR IMPROVING OUTCOMES FOR HEMATOPOIETIC CELL TRANSPLANT RECIPIENTS AT RISK FOR BRONCHIOLITIS OBLITERANS SYNDROME CHILDREN'S HOSPITAL MEDICAL CENTER 2025-08-21 US claimed
CN-119378927-B Toughness improvement method and system for power grid information physical fusion system 国网上海市电力公司 2025-04-29 CN claimed
WO-2024133913-A9 SEMIFLUORINATED ALKANE COMPOSITIONS COMPRISING HYOSCYAMINE NOVALIQ GMBH (DE) 2025-03-20 WO claimed
CN-119378927-A Toughness improvement method and system for power grid information physical fusion system 国网上海市电力公司 2025-01-28 CN claimed
WO-2024133913-A2 SEMIFLUORINATED ALKANE COMPOSITIONS COMPRISING HYOSCYAMINE NOVALIQ GMBH (DE) 2024-06-27 WO claimed
US-20240033258-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ADDICTION AND OTHER NEUROPSYCHIATRIC DISORDERS BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY & AGRICULTURAL & MECHANICAL COLLEGE (US) 2024-02-01 US claimed
CN-117474209-A Method, device, equipment and storage medium for analyzing electric power and economic and social association 国网能源研究院有限公司 2024-01-30 CN claimed
WO-2023212288-A1 METHODS FOR IMPROVING OUTCOMES FOR HEMATOPOIETIC CELL TRANSPLANT RECIPIENTS AT RISK FOR BRONCHIOLITIS OBLITERANS SYNDROME CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2023-11-02 WO claimed
EP-1143963-A1 MULTIPARTICULATE BISOPROLOL FORMULATION ATHPHARMA LIMITED (IE) 2001-10-17 EP claimed
WO-2000042998-A9 MULTIPARTICULATE BISOPROLOL FORMULATION ELAN CORP PLC (IE) 2001-05-25 WO claimed
WO-2000042998-A1 MULTIPARTICULATE BISOPROLOL FORMULATION ELAN CORPORATION, PLC (IE) 2000-07-27 WO claimed
EP-0641175-A4 DETERMINING BRAIN ACTIVITY INCLUDING THE NATURE OF BRAIN LESIONS BY ELECTROENCEPHALOGRAPHY. UNIV CALIFORNIA (US) 1995-01-05 EP claimed
WO-1991016545-A1 SELF-REGULATING DEVICE FOR THE LENGTH OF THE SECURITY BRAKE CABLE OF MOTOR VEHICLES PUJOL Y TARRAGO, S.A. (ES) 1991-10-31 WO claimed
EP-0399863-A1 Device for the introduction and the positioning of a tool into a pipe of a steam generator and use of that device FRAMATOME (FR) 1990-11-28 EP claimed
EP-0294248-A1 Method and apparatus for authorizing access to data or data communication lines DASSAULT AUTOMATISMES ET TELECOMMUNICATIONS (FR) 1988-12-07 EP claimed
EP-0229559-A1 Highly reliable computer-based network, and control method using the same CIMSA SINTRA (FR) 1987-07-22 EP claimed
EP-0144372-A1 INPUT/OUTPUT DEVICE CONNECTABLE TO THE CPU OF A PROGRAMMABLE AUTOMATIC CONTROLLER VIA A DATA AND ADDRESS BUS. TELEMECANIQUE ELECTRIQUE (FR) 1985-06-19 EP claimed
WO-1984004977-A1 METHOD AND DEVICE FOR THE PROTECTION AND MONITORING OF INFORMATION TRANSMISSION BETWEEN THE CENTRAL UNIT OF A PROGRAMMABLE COMPUTER AND THE SENSORS AND/OR ACTUATORS OF THE CONTROLLED PROCESS TELEMECANIQUE ELECTRIQUE (FR) 1984-12-20 WO claimed