Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | PARL | Q9H300 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13663246 | 1.00 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2APKML3MBTL1 | |
| SCHEMBL13663248 | 1.00 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2APKML3MBTL1 | |
| SCHEMBL113655 | 1.00 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2APKML3MBTL1 | |
| SCHEMBL113055 | 1.00 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2APKML3MBTL1 | |
| SCHEMBL2223806 | 1.00 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2APKML3MBTL1 | |
| SCHEMBL1325117 | 0.88 | MMP2 (0.55) | ALDH1A1MMP2SMN1; SMN2NPSR1 | |
| SCHEMBL8956550 | 0.88 | HTR6 (0.42) | ALDH1A1RAB9AKMT2AL3MBTL1CYP2C9 | |
| SCHEMBL9770675 | 0.87 | PTGS2 (0.41) | ALDH1A1RAB9AKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL8956525 | 0.84 | CYP3A4 (0.52) | ALDH1A1RAB9AKMT2ACYP2C9CYP3A4 | |
| SCHEMBL25735538 | 0.84 | LMNA (0.54) | ALDH1A1RAB9APKML3MBTL1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207704-A1 | Novel Oxadiazole Compounds | ABBOTT LABORATORIES (US) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207704-A1 | Novel Oxadiazole Compounds | S1PR3, S1PR1, S1PR2 | ALDH1A1 4044/4885RAB9A 2582/4885KMT2A 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.