Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23384529 | 0.78 | HSD11B1 (0.45) | HPGDALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL25629535 | 0.74 | LMNA (0.51) | HPGDL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL20722196 | 0.74 | ALDH1A1 (0.62) | LMNAALDH1A1KMT2AMAPTNPC1 | |
| SCHEMBL20739480 | 0.73 | S1PR1 (0.44) | KDM1AMAOBRCOR1HSD11B1 | |
| SCHEMBL609169 | 0.73 | CYP1A1 (0.51) | HPGDL3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL12656167 | 0.69 | KDM1A (0.36) | HPGDLMNAALDH1A1KDM1AMAOB | |
| SCHEMBL23384398 | 0.68 | ITGB3 (0.46) | HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL20739605 | 0.66 | S1PR1 (0.46) | HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL23912322 | 0.65 | HPGD (0.42) | HPGDL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL20739744 | 0.65 | S1PR1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032631-A1 | OXIME ETHER COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-02-14 | — | — | WO | disclosed |