Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12603984 | 0.83 | MAPK1 (0.54) | ALDH1A1SMN1; SMN2KDM4EMAPK1HSD11B1 | |
| SCHEMBL25185870 | 0.79 | KDM4E (0.48) | ALDH1A1SMN1; SMN2KDM4EMAPK1HSD11B1 | |
| SCHEMBL10391368 | 0.77 | MCL1 (0.66) | ALDH1A1SMN1; SMN2KDM4EMAPK1HSD11B1 | |
| SCHEMBL10391302 | 0.76 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4EMAPK1MEN1 | |
| SCHEMBL9108463 | 0.76 | DRD3 (0.48) | ALDH1A1SMN1; SMN2KDM4EMAPK1SLC2A1 | |
| SCHEMBL8967049 | 0.76 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KDM4EMAPK1SLC2A1 | |
| SCHEMBL29366129 | 0.75 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2KDM4EMAPK1CYP1A2 | |
| SCHEMBL52405 | 0.75 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2KDM4EMAPK1CYP1A2 | |
| SCHEMBL19612347 | 0.75 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4EMAPK1HSD11B1 | |
| SCHEMBL7461874 | 0.75 | MAPT (0.41) | ALDH1A1SMN1; SMN2KDM4EMAPK1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780935-B2 | Mutant antibodies and conjugation thereof | PFIZER HEALTHCARE IRELAND (IE) | 2023-10-10 | — | — | US | disclosed |
| US-20210147576-A1 | MUTANT ANTIBODIES AND CONJUGATION THEREOF | PFIZER HEALTHCARE IRELAND (IE) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147576-A1 | MUTANT ANTIBODIES AND CONJUGATION THEREOF | IGLV6-57, IGSF11, F13B | ALDH1A1 3691/4885SMN1; SMN2 2828/4885KDM4E 645/4885 |
| US-11780935-B2 | Mutant antibodies and conjugation thereof | IGLV6-57, IGSF11, F13B | ALDH1A1 3744/4885SMN1; SMN2 2832/4885KDM4E 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.