Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10391302 | 0.87 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL9108463 | 0.87 | DRD3 (0.48) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL976330 | 0.81 | KDM4E (0.57) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL669832 | 0.81 | THRB (0.61) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL6987407 | 0.80 | HSD17B10 (0.56) | ALDH1A1KDM4EHPGDHSD17B10DRD3 | |
| SCHEMBL485446 | 0.80 | KDM4E (0.47) | ALDH1A1KDM4EHPGDHSD17B10CDC25B | |
| SCHEMBL23725371 | 0.79 | HIF1A (0.48) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9110910 | 0.78 | MCL1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10CDC25B | |
| SCHEMBL8967046 | 0.78 | POLB (0.48) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL9978740 | 0.78 | MCL1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585116-B1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LTD (GB) | 1996-02-28 | — | — | EP | disclosed |
| US-5389684-A | Treats disorder of central nervous system | LILLY INDUSTRIES LIMITED (GB) | 1995-02-14 | — | — | US | disclosed |
| EP-0585116-A1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LIMITED (GB) | 1994-03-02 | — | — | EP | disclosed |