Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612487 | 0.86 | MAPT (0.44) | MAPTKMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL6474548 | 0.82 | MAPT (0.41) | MAPTKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL29363872 | 0.80 | ALDH1A1 (0.46) | MAPTKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL487367 | 0.80 | ALDH1A1 (0.46) | MAPTKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL1127920 | 0.78 | ALDH1A1 (0.44) | MAPTKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL19612241 | 0.78 | L3MBTL1 (0.47) | MAPTCYP1A2CYP2C19KDM4EL3MBTL1 | |
| SCHEMBL20398706 | 0.77 | MAPT (0.44) | MAPTKMT2AKDM4EL3MBTL1CSNK2A1 | |
| SCHEMBL19612685 | 0.76 | CNR1 (0.47) | MAPTKMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL20398447 | 0.75 | EPHX2 (0.42) | MAPTKMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL23271639 | 0.75 | ALDH1A1 (0.41) | MAPTCYP1A2CYP2C19KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020107278-A1 | Substituted azepino[4,5b]indole derivatives | PHARMACIA & UPJOHN COMPANY | 2002-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107278-A1 | Substituted azepino[4,5b]indole derivatives | HTR5A, HTR1A, HTR1E | MAPT 2666/4885KMT2A 2844/4885MEN1 852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.