SCHEMBL23401862

SCHEMBL23401862

CCn1nc(O)cc1-c1ccc(C(C)(C)C)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.43
PPARA Q07869 2/20 0.43
NR1H4 Q96RI1 1/20 0.43
TMEM97 Q5BJF2 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
ALDH1A1 P00352 3/20 0.39
HTT P42858 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSP90AA1 P07900 2/20 0.39
HSP90AB1 P08238 2/20 0.39
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MARS1 P56192 1/20 0.38
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402409 0.82 MARS1 (0.40) ALDH1A1KDM4ESMN1; SMN2NPC1TP53
SCHEMBL23401663 0.82 HDAC3 (0.41) ALDH1A1HTTKDM4EHPGDSMN1; SMN2
SCHEMBL23403521 0.80 SMPD1 (0.41) ALDH1A1KDM4ESMN1; SMN2NPC1MAPK1
SCHEMBL4692489 0.80 MARS1 (0.60) PPARGPPARANR1H4ALDH1A1HTT
SCHEMBL23399002 0.79 MCL1 (0.41) SMN1; SMN2NPC1TP53RAB9AMARS1
SCHEMBL23399772 0.77 GABRA1 (0.39) MARS1LMNAMAPTKMT2A
SCHEMBL23402917 0.77 HSD11B1 (0.43) ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2
SCHEMBL4692597 0.76 FAAH (0.57) PPARGPPARANPC1RAB9AMARS1
SCHEMBL23400794 0.72 NPC1 (0.41) ALDH1A1KDM4EHPGDNPC1TP53
SCHEMBL23403195 0.71 CNR1 (0.37) ALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed