Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 3/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864311 | 0.82 | ALDH1A1 (0.39) | RNPEPALDH1A1SLC7A5MEN1LMNA | |
| SCHEMBL2340644 | 0.79 | HSD17B10 (0.33) | CPA1MMEMMP1MMP3 | |
| SCHEMBL2239501 | 0.78 | CA1 (0.41) | RNPEPALDH1A1SLC7A5KISS1R | |
| SCHEMBL8705036 | 0.73 | RNPEP (0.38) | RNPEPALDH1A1SLC7A5MEN1LMNA | |
| SCHEMBL12570564 | 0.70 | RNPEP (0.39) | RNPEPALDH1A1SLC7A5 | |
| SCHEMBL6039560 | 0.69 | SLC7A5 (0.42) | RNPEPALDH1A1SLC7A5 | |
| SCHEMBL27617569 | 0.68 | GAA (0.54) | ALDH1A1LMNAKMT2A | |
| SCHEMBL6725243 | 0.67 | — | — | |
| SCHEMBL17949830 | 0.67 | CES2 (0.39) | RNPEPALDH1A1SLC7A5 | |
| SCHEMBL782702 | 0.66 | RNPEP (0.43) | RNPEPALDH1A1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534144-B1 | Preparation process of the sodium salt of Esomeprazole | ESTEVE QUÍMICA S A (ES) | 2014-09-03 | — | — | EP | disclosed |
| US-8680284-B2 | Preparation process of the sodium salt of esomeprazole | ESTEVE QUIMICA, S.A. (ES) | 2014-03-25 | — | — | US | disclosed |
| EP-2534144-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | Esteve Química, S.A. (ES) | 2012-12-19 | — | — | EP | disclosed |
| US-20120309976-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | Esteve Química, S.A. (ES) | 2012-12-06 | — | — | US | disclosed |
| WO-2011098553-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | Esteve Química, S.A. (ES) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309976-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | CYP2E1, ADH1C, ADH1A | RNPEP 1307/4885ALDH1A1 75/4885SLC7A5 659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.