Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.31 |
| ▸ | ACE | P12821 | 2/20 | 0.31 |
| ▸ | CPA1 | P15085 | 2/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.30 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15658171 | 0.83 | TDP1 (0.43) | HSD17B10CA1CA2CA7CA14 | |
| SCHEMBL15992208 | 0.82 | MMP1 (0.41) | HSD17B10CA1CA2CA7CA14 | |
| SCHEMBL28240252 | 0.80 | HAO1 (0.42) | — | |
| SCHEMBL2153461 | 0.79 | — | — | |
| SCHEMBL2340413 | 0.79 | RNPEP (0.38) | MMECPA1MMP1MMP3 | |
| SCHEMBL6914535 | 0.79 | LDHA (0.35) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL7948515 | 0.79 | ALDH1A1 (0.39) | CA2 | |
| SCHEMBL409846 | 0.75 | MMP1 (0.37) | HSD17B10CA1CA2CA7CA14 | |
| SCHEMBL410004 | 0.75 | ALDH1A1 (0.38) | HSD17B10CA1CA2CA7CA14 | |
| SCHEMBL518088 | 0.75 | LDHA (0.40) | MMEACECPA1ACE2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534144-B1 | Preparation process of the sodium salt of Esomeprazole | ESTEVE QUÍMICA S A (ES) | 2014-09-03 | — | — | EP | disclosed |
| US-8680284-B2 | Preparation process of the sodium salt of esomeprazole | ESTEVE QUIMICA, S.A. (ES) | 2014-03-25 | — | — | US | disclosed |
| EP-2534144-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | Esteve Química, S.A. (ES) | 2012-12-19 | — | — | EP | disclosed |
| US-20120309976-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | Esteve Química, S.A. (ES) | 2012-12-06 | — | — | US | disclosed |
| CN-102770423-A | Preparation process of the sodium salt of esomeprazole | ESTEVE QUIMICA SA | 2012-11-07 | — | — | CN | disclosed |
| WO-2011098553-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | Esteve Química, S.A. (ES) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309976-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | CYP2E1, ADH1C, ADH1A | HSD17B10 878/4885CA1 2718/4885CA2 1800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.