SCHEMBL2340469

SCHEMBL2340469

CCCCc1ccc(N2C=Cc3ccccc3C2[Ir](C2c3ccccc3C=CN2c2ccc(CCCC)cc2)C2c3ccccc3C=CN2c2ccc(CCCC)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.36
MGLL Q99685 1/20 0.36
HSD11B1 P28845 2/20 0.35
HTR2A P28223 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
KAT2B Q92831 2/20 0.32
TRPV1 Q8NER1 1/20 0.32
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
EP300 Q09472 1/20 0.31
KAT2A Q92830 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28981690 0.67 BRD4 (0.35) HTR2ABRD4CCL2ALDH1A1HPGD
SCHEMBL16390571 0.67 HTR6 (0.38) HSD11B1HTR2ACA1CA2ALDH1A1
SCHEMBL16389849 0.62 HTR2A (0.44) HTR2ALMNAALDH1A1HSD17B10
SCHEMBL83869 0.62 CA2 (0.65) MGLLHTR2ACA1CA2TRPV1
SCHEMBL30076246 0.61 MGLL (0.47) FAAHMGLLHSD11B1HTR2ACA1
SCHEMBL21272264 0.61 MGLL (0.47) FAAHMGLLHSD11B1HTR2ACA1
SCHEMBL6131261 0.61 ALDH1A1 (0.57) HSD11B1HTR2ACA1CA2TRPV1
SCHEMBL5602418 0.61 VHL (0.53) FAAHMGLLHSD11B1HTR2ACA1
Butylbenzyl SCHEMBL16051 0.60 SIGMAR1 (0.59) HSD11B1ALDH1A1HPGDHSD17B10
Butylbenzyl SCHEMBL22716183 0.60 SIGMAR1 (0.59) HSD11B1ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120211735-A1 ORGANIC EL ELEMENT AND ORGANIC LIGHT-EMITTING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-23 US disclosed
EP-2362460-A1 ORGANIC EL ELEMENT AND ORGANIC LIGHT-EMITTING DEVICE Mitsubishi Chemical Corporation (JP) 2011-08-31 EP disclosed