Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23405497 | 0.79 | POLB (0.62) | MAPTTP53POLBALDH1A1MEN1 | |
| SCHEMBL23405473 | 0.78 | POLB (0.54) | MAPTTP53POLBALDH1A1MEN1 | |
| SCHEMBL18385894 | 0.72 | KIT (0.54) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL10189660 | 0.70 | ALDH1A1 (0.61) | MAPTTP53ALDH1A1XBP1MEN1 | |
| SCHEMBL182604 | 0.69 | SRC (0.51) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL14619167 | 0.66 | MAPT (0.51) | MAPTTP53POLBALDH1A1MEN1 | |
| SCHEMBL182389 | 0.66 | PIK3CD (0.58) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL183411 | 0.66 | PIK3CD (0.58) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3587021 | 0.65 | CD274 (0.52) | MAPTTP53POLBALDH1A1XBP1 | |
| SCHEMBL548302 | 0.65 | POLB (0.69) | MAPTTP53POLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166611-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2024-05-23 | — | — | US | claimed |
| US-20210163425-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2021-06-03 | — | — | US | claimed |
| US-12297178-B2 | Triazole derivative and use thereof | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2025-05-13 | — | — | US | disclosed |
| US-20240166611-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2024-05-23 | — | — | US | disclosed |
| US-20210163425-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2021-06-03 | — | — | US | disclosed |
| US-20210163425-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163425-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | FABP4, LIPC, GPR119 | MAPT 2951/4885TP53 3433/4885POLB 4310/4885 |
| US-12297178-B2 | Triazole derivative and use thereof | FABP4, LIPC, GPR119 | MAPT 2945/4885TP53 3565/4885POLB 4363/4885 |
| US-20240166611-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | FABP4, LIPC, GPR119 | MAPT 2945/4885TP53 3565/4885POLB 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.