Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | SNCA | P37840 | 1/20 | 0.72 |
| ▸ | STS | P08842 | 3/20 | 0.60 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23557798 | 0.86 | HSD17B1 (0.76) | MAPTSNCASTSHSD17B1HSD17B2 | |
| SCHEMBL23405489 | 0.85 | MAPT (0.78) | MAPTSNCASTSHSD17B1HSD17B2 | |
| SCHEMBL23430997 | 0.84 | MAPT (0.77) | MAPTSNCAHSD17B1HSD17B2CA12 | |
| SCHEMBL12682333 | 0.84 | SNCA (1.00) | MAPTSNCAHSD17B1HSD17B2CA12 | |
| SCHEMBL23405494 | 0.83 | MAPT (0.81) | MAPTSNCAHSD17B1HSD17B2FLT3 | |
| SCHEMBL23405479 | 0.82 | MAPT (0.78) | MAPTSNCASTSHSD17B1HSD17B2 | |
| SCHEMBL23405482 | 0.82 | MAPT (0.83) | MAPTSNCASTSHSD17B1HSD17B2 | |
| SCHEMBL23405495 | 0.79 | MAPT (0.82) | MAPTSNCAHSD17B1HSD17B2CA12 | |
| SCHEMBL23405476 | 0.78 | MAPT (0.81) | MAPTSNCAHSD17B1HSD17B2NOTUM | |
| SCHEMBL18031112 | 0.78 | HSD17B1 (0.81) | MAPTSNCASTSHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12297178-B2 | Triazole derivative and use thereof | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2025-05-13 | — | — | US | claimed |
| US-20240166611-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2024-05-23 | — | — | US | claimed |
| US-20210163425-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2021-06-03 | — | — | US | claimed |
| US-12297178-B2 | Triazole derivative and use thereof | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2025-05-13 | — | — | US | disclosed |
| US-20240166611-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2024-05-23 | — | — | US | disclosed |
| US-20210163425-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2021-06-03 | — | — | US | disclosed |
| US-20210163425-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163425-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | FABP4, LIPC, GPR119 | MAPT 2951/4885SNCA 4775/4885STS 646/4885 |
| US-12297178-B2 | Triazole derivative and use thereof | FABP4, LIPC, GPR119 | MAPT 2945/4885SNCA 4771/4885STS 649/4885 |
| US-20240166611-A1 | TRIAZOLE DERIVATIVE AND USE THEREOF | FABP4, LIPC, GPR119 | MAPT 2945/4885SNCA 4771/4885STS 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.