SCHEMBL2340643

SCHEMBL2340643

c1cc(N2CCCO2)cc(N2CCCO2)c1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
KMO O15229 1/20 0.33
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
FAAH O00519 1/20 0.31
MGLL Q99685 1/20 0.31
AGXT P21549 2/20 0.31
MAPT P10636 1/20 0.31
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL363383 0.84 LMNA (0.45) LMNAALDH1A1KDM4EMEN1KMT2A
SCHEMBL27513171 0.78 LMNA (0.43) LMNAALDH1A1KDM4EMEN1GAA
SCHEMBL11593810 0.75 CHRNB2 (0.47)
SCHEMBL10648796 0.72 ADRB1 (0.39) LMNAALDH1A1KDM4EMEN1GAA
SCHEMBL28073187 0.72
SCHEMBL25293485 0.72 ALOX5 (0.33) LMNAALDH1A1KMT2AALOX5
SCHEMBL10515874 0.68 HTR3E (0.44) ALDH1A1KMT2AMGLLMAPT
SCHEMBL25286425 0.66 FFAR4 (0.35) ALDH1A1HPGDHSD17B10MAPT
SCHEMBL17027625 0.65 MEN1 (0.41) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL27329825 0.64 LMNA (0.71) LMNAKMOALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360215-A1 WATER-BASED INK FOR INKJET PRINTING Kao Corporation (JP) 2011-08-24 EP disclosed