Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CCKBR | P32239 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24240039 | 0.91 | MAPT (0.36) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23419323 | 0.75 | MAPT (0.44) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL24240023 | 0.75 | ITGB3 (0.33) | SRD5A1SRD5A2 | |
| SCHEMBL27215643 | 0.74 | AKR1B10 (0.34) | TP53SRD5A1SRD5A2POLB | |
| SCHEMBL23419400 | 0.73 | MAPT (0.42) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL26385373 | 0.72 | CCKBR (0.33) | LMNAHSD17B10CCKBR | |
| SCHEMBL23453249 | 0.72 | CCKBR (0.31) | LMNAHSD17B10CCKBR | |
| SCHEMBL23419154 | 0.72 | CCKBR (0.30) | CCKBR | |
| SCHEMBL25997626 | 0.71 | CCKBR (0.31) | LMNAHSD17B10CCKBR | |
| SCHEMBL24240022 | 0.71 | STS (0.34) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220033900-A1 | SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033900-A1 | SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS | FBL, DUT, PHAX | MAPT 3065/4885MEN1 4353/4885KMT2A 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.