Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342699 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TSHRTHRBLMNA | |
| SCHEMBL342569 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TSHRTHRBLMNA | |
| SCHEMBL233466 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TSHRTHRBLMNA | |
| SCHEMBL4970634 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TSHRTHRBLMNA | |
| SCHEMBL147883 | 0.98 | THRB (0.61) | ALDH1A1CYP3A4TSHRTHRBLMNA | |
| SCHEMBL146669 | 0.93 | THRB (0.63) | ALDH1A1CYP3A4TSHRTHRBLMNA | |
| SCHEMBL29315898 | 0.91 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRTHRBLMNA | |
| SCHEMBL29315894 | 0.91 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRTHRBLMNA | |
| SCHEMBL27929355 | 0.90 | THRB (0.59) | ALDH1A1CYP3A4TSHRTHRBLMNA | |
| SCHEMBL29315889 | 0.89 | THRB (0.55) | ALDH1A1CYP3A4TSHRTHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240142665-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2024-05-02 | — | — | US | claimed |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2024-04-11 | — | — | US | claimed |
| EP-4284787-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-12-06 | — | — | EP | claimed |
| EP-4263513-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-10-25 | — | — | EP | claimed |
| CN-116102283-B | Super-temperature-resistant high MB-value-resistant adsorption type polycarboxylate superplasticizer and preparation method thereof | 广西云鹰新材料科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116102283-A | Super-temperature-resistant high MB-value-resistant adsorption type polycarboxylate superplasticizer and preparation method thereof | 广西云鹰新材料科技有限公司 | 2023-05-12 | — | — | CN | claimed |
| EP-4036085-A1 | COMPOUNDS FOR OPTICALLY ACTIVE OPHTHALMIC DEVICES | AMO Ireland (IE) | 2022-08-03 | — | — | EP | claimed |
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | claimed |
| WO-2022128832-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | claimed |
| EP-4015512-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2022-06-22 | — | — | EP | claimed |
| US-20090093603-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON, INC. (CH) | 2009-04-09 | — | — | US | claimed |
| WO-2009046045-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYL ETHOXYLATE | ALCON, INC. (CH) | 2009-04-09 | — | — | WO | claimed |
| WO-2009046055-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYLPHENOL ETHOXYLATE | ALCON, INC. (CH) | 2009-04-09 | — | — | WO | claimed |
| US-20090093604-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON, INC. (CH) | 2009-04-09 | — | — | US | claimed |
| WO-2009046235-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON, INC. (CH) | 2009-04-09 | — | — | WO | claimed |
| WO-2009046232-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON, INC. (CH) | 2009-04-09 | — | — | WO | claimed |
| WO-2009046243-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON, INC. (CH) | 2009-04-09 | — | — | WO | claimed |
| US-20090088544-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYL ETHOXYLATE | ALCON, INC. (CH) | 2009-04-02 | — | — | US | claimed |
| US-20090088493-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYLPHENOL ETHOXYLATE | ALCON, INC. (CH) | 2009-04-02 | — | — | US | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, UACA, PDE6A | ALDH1A1 538/4885CYP3A4 3029/4885TSHR 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.