Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | GNPAT | O15228 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24235573 | 0.85 | KISS1R (0.41) | KISS1RSIRT6SIRT1FOLH1ALB | |
| SCHEMBL2628438 | 0.84 | NMT1 (0.49) | SIRT6SIRT1FOLH1NMT2NMT1 | |
| SCHEMBL13271590 | 0.84 | SIRT6 (0.44) | SIRT6SIRT1FOLH1NMT2NMT1 | |
| SCHEMBL23447289 | 0.83 | NOD1 (0.46) | KISS1RNMT2NMT1SLC6A5NOD1 | |
| SCHEMBL17483652 | 0.83 | KISS1R (0.40) | KISS1RSIRT6SIRT1FOLH1ALB | |
| SCHEMBL23447401 | 0.83 | NMT1 (0.51) | SIRT6SIRT1FOLH1NMT2NMT1 | |
| SCHEMBL2628439 | 0.83 | SIRT6 (0.45) | SIRT6SIRT1SLC6A5NOD1TLR2 | |
| SCHEMBL17526315 | 0.82 | SIRT6 (0.45) | KISS1RSIRT6SIRT1FOLH1ALB | |
| SCHEMBL23446572 | 0.82 | KISS1R (0.39) | KISS1RSIRT6SIRT1FOLH1ALB | |
| SCHEMBL18362334 | 0.81 | KISS1R (0.43) | KISS1RSIRT6SIRT1FOLH1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104120-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |