SCHEMBL234466

SCHEMBL234466

COC(=O)C1CCCCC1(CC1CO1)C(=O)OC

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.34
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28167487 0.80 TP53 (0.51) TP53CYP3A4ALDH1A1
SCHEMBL27452540 0.73
SCHEMBL11391765 0.72 TP53 (0.34) TP53CYP3A4ALDH1A1
SCHEMBL6429008 0.72 TP53 (0.33) TP53CYP3A4
SCHEMBL27207556 0.69 MAPT (0.41) TP53CYP3A4MAPTCYP4F2CYP4A11
SCHEMBL11508562 0.69
SCHEMBL28242611 0.67 PLG (0.30)
SCHEMBL11284836 0.67 ATM (0.40) MAPTNPSR1
SCHEMBL2000640 0.66 MAPT (0.38) MAPTCYP4F2CYP4A11NPSR1ALDH1A1
SCHEMBL7723055 0.66 TP53 (0.55) TP53CYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5990204-A HIGH HARDNESS; DIELECTRICS; SHEETING PROPERTIES; CORROSION RESISTANCE FOR METALS; GASKETS; SEALS; HARD BUTYL RUBBER ROLL; PACKING USED AT THE JOINT OF METAL PIPE; O-RING; PACKING FOR BATTERY; SEALS FOR ELECTROLYTIC CONDENSER ONIZAWA MASAO (JP) 1999-11-23 US claimed
EP-0353734-A2 Thermosetting composition NIPPON PAINT CO., LTD. (JP) 1990-02-07 EP claimed
US-12617753-B2 Urea derivatives and their use as curatives and curative accelerators for resin systems HEXCEL COMPOSITES LIMITED (GB) 2026-05-05 US disclosed
EP-4680659-A1 USE OF HYDROXY SUBSTITUTED URONES AS CURE ACCELERATORS Hexcel Composites Limited (GB) 2026-01-21 EP disclosed
EP-3959217-B1 IMPROVEMENTS IN OR RELATING TO CURATIVES HEXCEL COMPOSITES LTD (GB) 2025-10-15 EP disclosed
EP-4524197-A1 POLYALKYLENE TEREPHTHALATE RESIN COMPOSITION AND RESIN MOLDED ARTICLE Polyplastics Co., Ltd. (JP) 2025-03-19 EP disclosed
WO-2024194067-A1 USE OF HYDROXY SUBSTITUTED URONES AS CURE ACCELERATORS HEXCEL COMPOSITES LIMITED (GB) 2024-09-26 WO disclosed
US-20240262790-A1 UREA DERIVATIVES AND THEIR USE AS CURATIVES AND CURATIVE ACCELERATORS FOR RESIN SYSTEMS HEXCEL COMPOSITES LIMITED (GB) 2024-08-08 US disclosed
CN-116234846-B Resin composition and molded article 株式会社可乐丽 2024-07-02 CN disclosed
CN-116057043-B Urea derivatives and their use as curing agents and curing accelerators for resin systems 赫克塞尔合成有限公司 2024-04-16 CN disclosed
US-11939421-B2 Or relating to curing agents HEXCEL COMPOSITES LIMITED (GB) 2024-03-26 US disclosed
US-6388008-B2 DIELECTRIC, CORROSION RESISTANCE ONIZAWA MASAO (JP) 2002-05-14 US disclosed
US-20010031832-A1 Method for crosslinking of isoprene-isobutylene rubber and crosslinked rubber product obtained by said method ONIZAWA MASAO (JP) 2001-10-18 US disclosed
US-6255394-B1 INCREASING HARDNESS WITHOUT USING A HALOGEN COMPOUND OR EXCESS CARBON BLACK ONIZAWA MASAO (JP) 2001-07-03 US disclosed
US-6176965-B1 COATING ADHESIVE ONTO LUBRICATED PRESSED PLATE WITHOUT DEGREASING AND BONDING TO A STRUCTURAL MEMBER WHEREBY THE ADHESIVE COMPRISES DEHYDRATED ALUMINUM OR ZINC PHOSPHATE CHELATING AGENT, A LATENT CURING AGENT, AND AN EPOXY RESIN HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2001-01-23 US disclosed
US-5990204-A HIGH HARDNESS; DIELECTRICS; SHEETING PROPERTIES; CORROSION RESISTANCE FOR METALS; GASKETS; SEALS; HARD BUTYL RUBBER ROLL; PACKING USED AT THE JOINT OF METAL PIPE; O-RING; PACKING FOR BATTERY; SEALS FOR ELECTROLYTIC CONDENSER ONIZAWA MASAO (JP) 1999-11-23 US disclosed
US-5789354-A MODIFIED SILICONE OIL, CURING AGENT AND AN OIL OR GREASE NTN CORPORATION (JP) 1998-08-04 US disclosed
US-5762423-A Bearing device, solid resin lubricating composition and porous oil-impregnated bearing NTN CORPORATION (JP) 1998-06-09 US disclosed
US-5248559-A Laminates with lubricants HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 1993-09-28 US disclosed
EP-0353734-A2 Thermosetting composition NIPPON PAINT CO., LTD. (JP) 1990-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617753-B2 Urea derivatives and their use as curatives and curative accelerators for resin systems UTS2R, UPP1, XDH TP53 2646/4885CYP3A4 3441/4885MAPT 1337/4885
US-11939421-B2 Or relating to curing agents FABP4, RARA, ADIPOR1 TP53 1172/4885CYP3A4 3908/4885MAPT 3678/4885
US-20240262790-A1 UREA DERIVATIVES AND THEIR USE AS CURATIVES AND CURATIVE ACCELERATORS FOR RESIN SYSTEMS UMPS, UTS2R, UNG TP53 1511/4885CYP3A4 2959/4885MAPT 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.