Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.58 |
| ▸ | SNCA | P37840 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198508 | 0.86 | SNCA (0.62) | GPR35SNCAMAPTALDH1A1POLB | |
| SCHEMBL1736272 | 0.85 | POLB (0.62) | GPR35SNCAMAPTALDH1A1POLB | |
| SCHEMBL515466 | 0.84 | MAPT (0.54) | GPR35SNCAMAPTALDH1A1POLB | |
| SCHEMBL30279826 | 0.83 | GPR35 (0.56) | GPR35SNCAMAPTALDH1A1POLB | |
| SCHEMBL11328176 | 0.83 | GPR35 (0.56) | GPR35SNCAMAPTALDH1A1POLB | |
| SCHEMBL5175273 | 0.83 | GPR35 (0.56) | GPR35SNCAMAPTALDH1A1POLB | |
| SCHEMBL4962677 | 0.83 | GPR35 (0.56) | GPR35SNCAMAPTALDH1A1POLB | |
| SCHEMBL10680353 | 0.83 | GPR35 (0.56) | GPR35SNCAMAPTALDH1A1POLB | |
| SCHEMBL8063487 | 0.83 | GPR35 (0.56) | GPR35SNCAMAPTALDH1A1POLB | |
| SCHEMBL15466784 | 0.81 | GPR35 (0.55) | GPR35SNCAMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947677-B | Prodrug compound and preparation method and application thereof | 湖南工程学院 | 2024-07-23 | — | — | CN | claimed |
| US-12459883-B2 | Substituted hydroxystilbene compounds and derivatives synthesis and uses thereof | Kynan Duke IP, LLC (US) | 2025-11-04 | — | — | US | disclosed |
| CN-115947677-B | Prodrug compound and preparation method and application thereof | 湖南工程学院 | 2024-07-23 | — | — | CN | disclosed |
| CN-115417859-B | Synthesis method of rizatriptan benzoate | 陕西师范大学 | 2024-02-02 | — | — | CN | disclosed |
| US-11807621-B2 | Compounds and compositions for use in treating skin disorders | KAMARI PHARMA LTD. (IL) | 2023-11-07 | — | — | US | disclosed |
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | Kynan Duke IP, LLC (US) | 2023-05-25 | — | — | US | disclosed |
| CN-115485259-A | Substituted hydroxystilbene compounds and derivatives, synthesis and use thereof | 凯楠公爵IP有限责任公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-113912853-A | Self-depolymerizing polymer, nano-particle based on self-depolymerizing polymer and application thereof | 中国科学技术大学 | 2022-01-11 | — | — | CN | disclosed |
| WO-2021127743-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | Kynan Duke IP, LLC (US) | 2021-07-01 | — | — | WO | disclosed |
| CN-107207444-B | Bicyclic compounds | 武田药品工业株式会社 | 2020-07-24 | — | — | CN | disclosed |
| EP-1163220-A1 | TRICYCLIC INDOLE-2-CARBOXYLIC ACID COMPOUND USED AS NMDA RECEPTOR ANTAGONIST | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-6140041-A | Fluorescent dye | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-10-31 | — | — | US | disclosed |
| WO-2000056711-A1 | TRICYCLIC INDOLE-2-CARBOXYLIC ACID COMPOUND USED AS NMDA RECEPTOR ANTAGONIST | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2000-09-28 | — | — | WO | disclosed |
| US-5958673-A | Fluorescent dye | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-09-28 | — | — | US | disclosed |
| WO-1999038919-A1 | FLUORESCENT DYE | NOVARTIS AG (CH) | 1999-08-05 | — | — | WO | disclosed |
| US-5599913-A | COMPLEXES | HARRIS STEPHEN J (IE) | 1997-02-04 | — | — | US | disclosed |
| WO-1994004483-A1 | CHROMOGENIC LIGANDS AND USE THEREOF IN OPTICAL SENSORS | HARRIS STEPHEN JOHN (IE) | 1994-03-03 | — | — | WO | disclosed |
| EP-0581464-A1 | Ester derivatives and pharmaceutical compositions containing them | ZENECA LIMITED (GB) | 1994-02-02 | — | — | EP | disclosed |
| US-5274002-A | 1-Oxy- or -thio-2-cycloalkyloxy-4-carboxyalkylene benzene derivatives | WARNER-LAMBERT COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| US-4971959-A | Trisubstituted phenyl analogs having activity for congestive heart failure | WARNER-LAMBERT COMPANY (US) | 1990-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12459883-B2 | Substituted hydroxystilbene compounds and derivatives synthesis and uses thereof | CYP8B1, HSD11B1, HSD11B2 | GPR35 930/4885SNCA 2440/4885MAPT 3957/4885 |
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | CYP8B1, HSD11B1, HSD11B2 | GPR35 930/4885SNCA 2440/4885MAPT 3957/4885 |
| US-11807621-B2 | Compounds and compositions for use in treating skin disorders | RDX, HAX1, F12 | GPR35 3192/4885SNCA 3740/4885MAPT 3652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.