Sugi Predict

Sugi Predict / Compounds / SCHEMBL2345581

SCHEMBL2345581

SCHEMBL2345581

CCOC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 2/20 1.00
▸ PTGS1 P23219 3/20 0.52
▸ PTGS2 P35354 3/20 0.52
▸ USP2 O75604 2/20 0.52
▸ KDM4E B2RXH2 2/20 0.52
▸ CYP1A2 P05177 1/20 0.52
▸ CYP3A4 P08684 1/20 0.52
▸ CYP2D6 P10635 1/20 0.52
▸ CYP2C9 P11712 1/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ NFKB1 P19838 1/20 0.52
▸ CYP2C19 P33261 1/20 0.52
▸ BLM P54132 1/20 0.52
▸ SLC22A6 Q4U2R8 1/20 0.52
▸ SLC22A8 Q8TCC7 1/20 0.52
▸ LMNA P02545 1/20 0.52
▸ KDR P35968 1/20 0.52
▸ MAPK1 P28482 1/20 0.51
▸ ABCB11 O95342 1/20 0.51
▸ GLA P06280 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30822800 1.00 HSD11B1 (1.00) HSD11B1PTGS1PTGS2USP2KDM4E
SCHEMBL10954111 0.90 HSD11B1 (0.81) HSD11B1PTGS1PTGS2USP2KDM4E
SCHEMBL10954905 0.87 HSD11B1 (0.77) HSD11B1PTGS1PTGS2USP2KDM4E
SCHEMBL10508168 0.87 HSD11B1 (0.77) HSD11B1PTGS1PTGS2USP2KDM4E
SCHEMBL10958289 0.86 HSD11B1 (0.75) HSD11B1PTGS1PTGS2USP2KDM4E
SCHEMBL10964170 0.86 HSD11B1 (0.75) HSD11B1PTGS1PTGS2USP2KDM4E
SCHEMBL9983115 0.86 HSD11B1 (0.74) HSD11B1USP2CYP3A4CYP2C9CYP2C19
SCHEMBL11034692 0.85 HSD11B1 (0.73) HSD11B1PTGS1PTGS2USP2KDM4E
SCHEMBL6796426 0.85 HSD11B1 (0.73) HSD11B1PTGS1PTGS2USP2KDM4E
SCHEMBL30218271 0.85 HSD11B1 (0.73) HSD11B1PTGS1PTGS2USP2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324757-A Meloxicam production method 山东新华制药股份有限公司 2024-07-12 — — CN claimed
US-4478996-A Process for the preparation of 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxides MEDICHEM, S.A. (ES) 1984-10-23 — — US claimed
US-20250195535-A1 PHARMACEUTICAL LIQUID COMPOSITIONS OF MELOXICAM SLAYBACK PHARMA LLC (US) 2025-06-19 — — US disclosed
US-12263176-B2 Pharmaceutical liquid compositions of meloxicam SLAYBACK PHARMA LLC (US) 2025-04-01 — — US disclosed
CN-118324757-A Meloxicam production method 山东新华制药股份有限公司 2024-07-12 — — CN disclosed
US-20240139204-A1 PHARMACEUTICAL LIQUID COMPOSITIONS OF MELOXICAM SLAYBACK PHARMA LLC (US) 2024-05-02 — — US disclosed
US-20220249507-A1 PHARMACEUTICAL LIQUID COMPOSITIONS OF MELOXICAM ARBOR PHARMACEUTICALS, LLC 2022-08-11 — — US disclosed
US-20220008337-A1 PHARMACEUTICAL LIQUID COMPOSITIONS OF MELOXICAM ARBOR PHARMACEUTICALS, LLC 2022-01-13 — — US disclosed
US-20220002283-A1 MELOXICAM CO-CRYSTALS MYLAN LABORATORIES LIMITED (IN) 2022-01-06 — — US disclosed
CN-113614077-A Meloxicam cocrystal 迈兰实验室有限公司 2021-11-05 — — CN disclosed
EP-3877385-A1 MELOXICAM CO-CRYSTALS Mylan Laboratories Ltd. (IN) 2021-09-15 — — EP disclosed
EP-0049099-B1 SYNTHETIC METHOD AND INTERMEDIATE FOR PIROXICAM PFIZER INC. (US) 1985-07-17 — — EP disclosed
EP-0049099-A2 Synthetic method and intermediate for piroxicam PFIZER INC. (US) 1982-04-07 — — EP disclosed
US-4289879-A Synthetic method and intermediate for piroxicam PFIZER INC. (US) 1981-09-15 — — US disclosed
US-4233299-A ANTIINFLAMMATORY AGENTS, ANTIPYRETICS BOEHRINGER INGELHEIM GMBH (DE) 1980-11-11 — — US disclosed
US-RE29836-E 4-Hydroxy-3-(3-isoxazolylcarbamoyl)-2H-1,2-benzothiazine 1,1-dioxides and process for their production WARNER-LAMBERT COMPANY (US) 1978-11-14 — — US disclosed
US-4062968-A MITICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-12-13 — — US disclosed
US-4039680-A SULFUR CONTAINING HETEROCYCLES SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-02 — — US disclosed
US-4031235-A Insecticidal substituted acetate compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-21 — — US disclosed
US-3937828-A Substituted pyrano[3,2-c] [1,2]benzothiazine 6,6-dioxides WARNER-LAMBERT COMPANY (US) 1976-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220008337-A1 PHARMACEUTICAL LIQUID COMPOSITIONS OF MELOXICAM P2RY12, P2RY10, P2RY6 HSD11B1 2671/4885PTGS1 45/4885PTGS2 127/4885
US-20250195535-A1 PHARMACEUTICAL LIQUID COMPOSITIONS OF MELOXICAM P2RY12, P2RY10, P2RY6 HSD11B1 2671/4885PTGS1 45/4885PTGS2 127/4885
US-12263176-B2 Pharmaceutical liquid compositions of meloxicam P2RY12, P2RY10, P2RY6 HSD11B1 2671/4885PTGS1 45/4885PTGS2 127/4885
US-20220249507-A1 PHARMACEUTICAL LIQUID COMPOSITIONS OF MELOXICAM P2RY12, P2RY10, P2RY6 HSD11B1 2671/4885PTGS1 45/4885PTGS2 127/4885
US-20240139204-A1 PHARMACEUTICAL LIQUID COMPOSITIONS OF MELOXICAM P2RY12, P2RY10, P2RY6 HSD11B1 2671/4885PTGS1 45/4885PTGS2 127/4885
US-20220002283-A1 MELOXICAM CO-CRYSTALS MGAM, MGAM2, MLX HSD11B1 2179/4885PTGS1 337/4885PTGS2 280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.