Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3860756 | 1.00 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL23457832 | 1.00 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3496397 | 0.81 | ALDH1A1 (0.43) | L3MBTL1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL29993269 | 0.79 | CTSL (0.53) | L3MBTL1MEN1KMT2APKMPOLB | |
| SCHEMBL17819830 | 0.77 | MEN1 (0.44) | L3MBTL1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL20568365 | 0.77 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1SMN1; SMN2TSHRGLA | |
| SCHEMBL3494455 | 0.77 | FKBP1A (0.59) | MEN1KMT2AALDH1A1HPGDPKM | |
| SCHEMBL3859663 | 0.77 | FKBP1A (0.61) | MEN1KMT2AALDH1A1HPGDPKM | |
| SCHEMBL554903 | 0.77 | FKBP1A (0.61) | MEN1KMT2AALDH1A1HPGDPKM | |
| SCHEMBL10058357 | 0.76 | MEN1 (0.55) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110968-A1 | MACROCYLCES COMPRISING A 4-AMIDO-2,4-PENTADIENOATE MOIETY FOR THE TREATMENT OF HYPOXIC CANCERS | AARHUS UNIVERSITET (DK) | 2021-06-10 | — | — | WO | disclosed |