Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3810263 | 0.73 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1ARG1 | |
| SCHEMBL4314338 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1POLBARG1 | |
| SCHEMBL4846610 | 0.71 | TP53 (0.37) | FGFR1TP53HBBSMN1; SMN2BRD4 | |
| SCHEMBL13063787 | 0.71 | TP53 (0.37) | FGFR1TP53HBBSMN1; SMN2BRD4 | |
| SCHEMBL27845254 | 0.70 | TLR8 (0.42) | SMN1; SMN2ALDH1A1POLBARG1 | |
| SCHEMBL28113341 | 0.70 | CYP1A2 (0.46) | FGFR1TP53HBBSMN1; SMN2BRD4 | |
| SCHEMBL31210326 | 0.70 | ARG1 (0.39) | SMN1; SMN2ALDH1A1ARG1 | |
| SCHEMBL4325015 | 0.70 | SIRT2 (0.38) | ALDH1A1ARG1 | |
| SCHEMBL4319831 | 0.70 | KDM4E (0.41) | SMN1; SMN2ALDH1A1POLBARG1 | |
| SCHEMBL7362579 | 0.69 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110893-A1 | PROCESS AND INTERMEDIATES FOR THE PRODUCTION OF FORMULA (I) | ASTRAZENECA AB (SE) | 2021-06-10 | — | — | WO | claimed |
| WO-2021110893-A1 | PROCESS AND INTERMEDIATES FOR THE PRODUCTION OF FORMULA (I) | ASTRAZENECA AB (SE) | 2021-06-10 | — | — | WO | disclosed |