Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAP2K3 | P46734 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31210326 | 0.85 | ARG1 (0.39) | ALDH1A1ARG1SMN1; SMN2MAP2K3ESR1 | |
| SCHEMBL4314338 | 0.81 | SMN1; SMN2 (0.39) | ALDH1A1ARG1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27845254 | 0.78 | TLR8 (0.42) | ALDH1A1ARG1SMN1; SMN2FLT1KDR | |
| SCHEMBL4333586 | 0.77 | SMN1; SMN2 (0.33) | ALDH1A1ARG1SMN1; SMN2ESR1RAB9A | |
| SCHEMBL7362579 | 0.77 | ALDH1A1 (0.33) | ALDH1A1ARG1SMN1; SMN2ESR1RAB9A | |
| SCHEMBL18839651 | 0.75 | KDM4E (0.44) | ALDH1A1SMN1; SMN2NPC1KDM4EOPRK1 | |
| SCHEMBL4327360 | 0.75 | HTT (0.33) | ALDH1A1ARG1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4325015 | 0.74 | SIRT2 (0.38) | ALDH1A1ARG1OPRD1OPRK1 | |
| SCHEMBL3313595 | 0.74 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL10421136 | 0.74 | F13A1 (0.40) | ALDH1A1ARG1SMN1; SMN2ESR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042514-A1 | NANOPORE AND CARBON NANOTUBE BASED DNA SEQUENCER AND A SERIAL RECOGNITION ELEMENTS | ARIZONA BOARD OF REGENTS (US) | 2010-04-15 | — | — | WO | disclosed |