SCHEMBL2345848

SCHEMBL2345848

O=[N+]([O-])c1ccc(S(=O)(=O)C2CCCC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.51
CA1 P00915 5/20 0.50
CA2 P00918 5/20 0.50
CA12 O43570 4/20 0.50
CA9 Q16790 4/20 0.50
CA14 Q9ULX7 4/20 0.50
CA3 P07451 3/20 0.50
CA4 P22748 3/20 0.50
CA6 P23280 3/20 0.50
CA5A P35218 3/20 0.50
CA7 P43166 3/20 0.50
CA13 Q8N1Q1 3/20 0.50
CA5B Q9Y2D0 3/20 0.50
POLB P06746 2/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
DDIT3 P35638 1/20 0.48
TXNRD1 Q16881 3/20 0.48
GSR P00390 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20379733 0.98 ACHE (0.50) ACHECA1CA2CA12CA9
SCHEMBL2148897 0.92 CA2 (0.53) ACHECA1CA2CA12CA9
SCHEMBL21533037 0.87 DDIT3 (0.43) ACHECA1CA2CA12CA9
SCHEMBL1870250 0.84 ADRB1 (0.46) ACHECA1CA2CA12CA9
SCHEMBL2632975 0.84 DDIT3 (0.53) ACHECA1CA2CA12CA9
SCHEMBL12280404 0.84 DDIT3 (0.44) ACHEDDIT3TXNRD1GSRMMP1
Hydrochloric Acid SCHEMBL30005551 0.83 ADRB1 (0.45) ACHECA1CA2CA12CA9
SCHEMBL10799341 0.82 APLNR (0.44) ACHECA1CA2CA12CA9
SCHEMBL17373706 0.82 SIRT6 (0.51) ACHECA1CA2CA12CA9
Hydrochloric Acid SCHEMBL10795736 0.81 ACHE (0.43) ACHECA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250381317-A1 COLLAGEN COMPOSITIONS AND METHODS OF USE THEREOF MODERN MEADOW INC (US) 2025-12-18 US disclosed
EP-4531795-A2 COLLAGEN COMPOSITIONS AND METHODS OF USE THEREOF HTL Biotechnology Innovation, Inc. (US) 2025-04-09 EP disclosed
CN-119562802-A Collagen compositions and methods of use thereof HTL生物创新股份有限公司 2025-03-04 CN disclosed
CN-117897058-A Collagen compositions and methods of use thereof 现代牧场股份有限公司 2024-04-16 CN disclosed
US-20240099955-A1 SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF HTL BIOTECHNOLOGY INNOVATION INC. 2024-03-28 US disclosed
EP-4329521-A2 COLLAGEN COMPOSITIONS AND METHODS OF USE THEREOF Modern Meadow, Inc. (US) 2024-03-06 EP disclosed
EP-4288084-A1 SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF Modern Meadow, Inc. (US) 2023-12-13 EP disclosed
WO-2023235775-A2 COLLAGEN COMPOSITIONS AND METHODS OF USE THEREOF MODERN MEADOW, INC. (US) 2023-12-07 WO disclosed
CN-116847871-A Skin care compositions and methods of use 现代牧场股份有限公司 2023-10-03 CN disclosed
WO-2022232566-A2 COLLAGEN COMPOSITIONS AND METHODS OF USE THEREOF MODERN MEADOW, INC. (US) 2022-11-03 WO disclosed
US-20070142373-A1 Quinoline derivatives as phosphodiesterase inhibitors GLAXO GROUP LIMITED (GB) 2007-06-21 US disclosed
US-20070142373-A1 Quinoline derivatives as phosphodiesterase inhibitors GLAXO GROUP LIMITED (GB) 2007-06-21 US disclosed
US-20070142373-A1 Quinoline derivatives as phosphodiesterase inhibitors GLAXO GROUP LIMITED (GB) 2007-06-21 US disclosed
US-20070049570-A1 Quinoline derivatives as phosphodiesterase inhibitors DEAN ANTHONY W 2007-03-01 US disclosed
US-20070049570-A1 Quinoline derivatives as phosphodiesterase inhibitors DEAN ANTHONY W 2007-03-01 US disclosed
US-20070049570-A1 Quinoline derivatives as phosphodiesterase inhibitors DEAN ANTHONY W 2007-03-01 US disclosed
US-20060178416-A1 Quinoline derivatives as phosphodiesterase inhibitors BARKER MICHAEL D 2006-08-10 US disclosed
EP-1633748-A1 QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LIMITED (GB) 2006-03-15 EP disclosed
WO-2004103998-A1 QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LIMITED (GB) 2004-12-02 WO disclosed
WO-2004103998-A1 QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LIMITED (GB) 2004-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060178416-A1 Quinoline derivatives as phosphodiesterase inhibitors PDE3B, PDE4B, PDE4A ACHE 32/4885CA1 4500/4885CA2 1594/4885
US-20070049570-A1 Quinoline derivatives as phosphodiesterase inhibitors PDE3B, PDE4B, PDE4A ACHE 32/4885CA1 4500/4885CA2 1594/4885
US-20070142373-A1 Quinoline derivatives as phosphodiesterase inhibitors PDE3B, PDE4B, PDE4A ACHE 32/4885CA1 4500/4885CA2 1594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.