Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19330053 | 0.73 | MMP12 (0.38) | RPS6KA3ALDH1A1KDM4EGAATP53 | |
| SCHEMBL5144295 | 0.71 | TLR8 (0.44) | EGFRALDH1A1KDM4EGAATSHR | |
| SCHEMBL23876533 | 0.71 | EGFR (0.37) | EGFRALDH1A1KDM4EGAATP53 | |
| SCHEMBL23459663 | 0.69 | KDM4E (0.47) | ALDH1A1KDM4EGAATP53HPGD | |
| SCHEMBL23459660 | 0.69 | PRMT5 (0.40) | EGFRALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL15910605 | 0.68 | KDM4E (0.37) | RPS6KA3ALDH1A1KDM4EGAARAD52 | |
| SCHEMBL17686232 | 0.65 | BRD2 (0.37) | RPS6KA3ALDH1A1KDM4ETP53TSHR | |
| SCHEMBL1285878 | 0.63 | RPS6KA3 (0.58) | RPS6KA3ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL23459661 | 0.62 | NOS2 (0.34) | — | |
| SCHEMBL15174271 | 0.61 | RPS6KA5 (0.41) | EGFRALDH1A1KDM4EGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021105481-A1 | NOVEL COMPOUNDS FOR TREATMENT OF DISEASES RELATED TO DUX4 EXPRESSION | Facio Intellectual Property B.V. (NL) | 2021-06-03 | — | — | WO | disclosed |