Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145732 | 0.81 | NR1H2 (0.41) | ALDH1A1KDM4ENPC1RAB9AGAA | |
| SCHEMBL5146857 | 0.81 | CYP11B2 (0.40) | ALDH1A1KDM4ENOS2NPC1RAB9A | |
| SCHEMBL353025 | 0.78 | CYP1A2 (0.59) | TLR8CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5144279 | 0.76 | DAO (0.41) | TLR8CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14304355 | 0.76 | TLR8 (0.41) | TLR8CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5928692 | 0.74 | KDM4E (0.60) | ALDH1A1KDM4ENPC1RAB9AHTR3A | |
| Formamide SCHEMBL28367514 | 0.73 | CYP1A2 (0.51) | TLR8CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14247767 | 0.73 | HTR6 (0.40) | TLR8CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15112010 | 0.73 | KMT2A (0.40) | TLR8CYP1A2CYP3A4CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL28791312 | 0.72 | KMT2A (0.39) | TLR8CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108707140-B | Protease C inhibitors | 勃林格殷格翰国际有限公司 | 2022-07-22 | — | — | CN | disclosed |
| EP-3866216-A1 | ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME | Samsung Display Co., Ltd. (KR) | 2021-08-18 | — | — | EP | disclosed |
| US-20200039961-A1 | SUBSTITUTED FUSED BI- OR TRI- HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS | Epizyme, Inc. | 2020-02-06 | — | — | US | disclosed |
| CN-108707140-A | Protease C inhibitor | 勃林格殷格翰国际有限公司 | 2018-10-26 | — | — | CN | disclosed |
| CN-105026395-B | Substituted azabicyclic amide cathepsin C inhibitor, pharmaceutical composition and pharmaceutical application thereof | 勃林格殷格翰国际有限公司 | 2018-07-20 | — | — | CN | disclosed |
| CN-105026395-A | Substituted 2-aza-bicyclo [2.2.1] heptane-3-carboxylic acid (benzyl-cyano-methyl) -amide cathepsin C inhibitors | BOEHRINGER INGELHEIM INT | 2015-11-04 | — | — | CN | disclosed |
| US-20070269664-A1 | Gas Barrier Laminated Film and Process for Producing the Same | SAI NIPPON PRINTING CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| WO-2005108374-A1 | INSECTICIDAL DIAZOLE AND TRIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2005-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070269664-A1 | Gas Barrier Laminated Film and Process for Producing the Same | CDH1, VIL1, TET1 | TLR8 1854/4885CYP1A2 2849/4885CYP3A4 2668/4885 |
| US-20200039961-A1 | SUBSTITUTED FUSED BI- OR TRI- HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS | SHMT1, BHMT, EHMT2 | TLR8 4653/4885CYP1A2 1451/4885CYP3A4 2092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.