Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL21268603 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL9014347 | 0.74 | DAO (0.32) | — | |
| SCHEMBL307607 | 0.73 | CA12 (0.45) | CES2CES1 | |
| SCHEMBL4184604 | 0.72 | TUBB1 (0.36) | — | |
| SCHEMBL667921 | 0.72 | CES2 (0.36) | CES2CES1 | |
| SCHEMBL19031224 | 0.72 | — | — | |
| SCHEMBL31048580 | 0.71 | CES2 (0.36) | CES2CES1KAT2B | |
| SCHEMBL5859934 | 0.71 | CA1 (0.33) | CES2CES1 | |
| SCHEMBL29185156 | 0.71 | CES2 (0.36) | CES2CES1KAT2B | |
| Bromide SCHEMBL733561 | 0.70 | CES2 (0.34) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119236835-B | Continuous reaction system and continuous method for producing 3',4',5' -trifluoro-biphenyl-2-amine | 天津凯莱英医药科技发展有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119236835-A | Continuous reaction system and continuous method for producing 3',4',5' -trifluoro-biphenyl-2-amine | 天津凯莱英医药科技发展有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-109761820-B | Chemical synthesis method of 3',4',5 '-trifluoro- [1,1' -biphenyl ] -2-amine | 浙江工业大学 | 2022-03-25 | — | — | CN | claimed |
| CN-100548950-C | Process for preparing esters and ethers of probucol and derivatives thereof | ATHEROGENICS INC (US) | 2009-10-14 | — | — | CN | claimed |
| US-7098344-B2 | Reaction of carbonyl compounds with organometallic reagents | MERCK PATENT GMBH (DE) | 2006-08-29 | — | — | US | claimed |
| CN-1759084-A | Process for preparing esters and ethers of probucol and derivatives thereof | ATHEROGENICS INC (US) | 2006-04-12 | — | — | CN | claimed |
| US-20040204485-A1 | Process of preparing esters and ethers of probucol and derivatives thereof | CRABTREE ACQUISITION CO, LLC | 2004-10-14 | — | — | US | claimed |
| US-20030004357-A1 | Reaction of carbonyl compounds with organometallic reagents | MERCK PATENT GMBH (DE) | 2003-01-02 | — | — | US | claimed |
| US-12410271-B1 | CO2 chemical reaction viscosity-increasing type polymer surfactant for gas channeling control during CO2 flooding in offshore heavy oil reservoirs, preparation method therefor and use thereof | CHINA UNIVERSITY OF PETROLEUM (EAST CHINA) (CN) | 2025-09-09 | — | — | US | disclosed |
| EP-4536362-A1 | TRICYCLIC TRIAZOLO COMPOUNDS AS DGK INHIBITORS | Incyte Corporation (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-119661570-A | CO (carbon monoxide)2Lewis acid monomer for reaction adhesion-promoting type surface polymerization agent and preparation method thereof | 中国石油大学(华东) | 2025-03-21 | — | — | CN | disclosed |
| CN-119613611-A | Be used for marine CO2CO for controlling thick oil and gas channeling2Chemical reaction adhesion-promoting type surface-accumulating agent, and preparation method and application thereof | 中国石油大学(华东) | 2025-03-14 | — | — | CN | disclosed |
| CN-119236835-B | Continuous reaction system and continuous method for producing 3',4',5' -trifluoro-biphenyl-2-amine | 天津凯莱英医药科技发展有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119236835-A | Continuous reaction system and continuous method for producing 3',4',5' -trifluoro-biphenyl-2-amine | 天津凯莱英医药科技发展有限公司 | 2025-01-03 | — | — | CN | disclosed |
| EP-0711777-B1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHINETSU CHEMICAL CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-1053239-A1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999041256-A1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1999-08-19 | — | — | WO | disclosed |
| EP-0623102-B1 | CYCLOBUTANE-BENZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 1998-06-24 | — | — | EP | disclosed |
| EP-0711777-A1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5445764-A | Based on derivatives of m-difluorobenzene; low viscosity; stability; broad mesophase range; good optical and dielectric anisotropy; specific resistance; matrix and supertwist displays | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004357-A1 | Reaction of carbonyl compounds with organometallic reagents | CBR3, ME3, GLRX3 | CES2 3223/4885CES1 4491/4885KAT2B 421/4885 |
| US-20040204485-A1 | Process of preparing esters and ethers of probucol and derivatives thereof | NR3C2, MGLL, GCG | CES2 562/4885CES1 439/4885KAT2B 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.