Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2345186 | 0.82 | ACHE (0.36) | CA12CA1CA9 | |
| SCHEMBL1923653 | 0.82 | RAPGEF4 (0.32) | CA12CA1CA9 | |
| Tetrahydrofuran SCHEMBL21268604 | 0.82 | ALDH1A1 (0.33) | CA12CA1CA9 | |
| SCHEMBL20184807 | 0.78 | RXRA (0.33) | CES2 | |
| SCHEMBL2347207 | 0.73 | CES2 (0.36) | CES2CES1 | |
| Iodide SCHEMBL1864364 | 0.71 | ACHE (0.41) | CES2CES1 | |
| SCHEMBL449836 | 0.71 | — | — | |
| SCHEMBL19031224 | 0.69 | — | — | |
| SCHEMBL137718 | 0.69 | — | — | |
| SCHEMBL14763721 | 0.69 | CA12 (0.38) | CA12CA1CA9CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 470 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025242747-A1 | MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS | MERCK PATENT GMBH (DE) | 2025-11-27 | — | — | WO | claimed |
| CN-119661570-A | CO (carbon monoxide)2Lewis acid monomer for reaction adhesion-promoting type surface polymerization agent and preparation method thereof | 中国石油大学(华东) | 2025-03-21 | — | — | CN | claimed |
| CN-118108571-A | Synthesis method of 3, 5-difluoroethylbenzene | 中国船舶集团有限公司第七一八研究所 | 2024-05-31 | — | — | CN | claimed |
| CN-100548950-C | Process for preparing esters and ethers of probucol and derivatives thereof | ATHEROGENICS INC (US) | 2009-10-14 | — | — | CN | claimed |
| US-7273948-B2 | Process of preparing esters and ethers of probucol and derivatives thereof | ATHEROGENICS, INC. (US) | 2007-09-25 | — | — | US | claimed |
| EP-1594824-A4 | PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF | ATHEROGENICS INC (US) | 2007-04-04 | — | — | EP | claimed |
| CN-1759084-A | Process for preparing esters and ethers of probucol and derivatives thereof | ATHEROGENICS INC (US) | 2006-04-12 | — | — | CN | claimed |
| EP-1594824-A2 | PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF | Atherogenics, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| US-20040204485-A1 | Process of preparing esters and ethers of probucol and derivatives thereof | CRABTREE ACQUISITION CO, LLC | 2004-10-14 | — | — | US | claimed |
| WO-2004062622-A2 | PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF | ATHEROGENICS, INC. (US) | 2004-07-29 | — | — | WO | claimed |
| WO-2025242747-A1 | MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS | MERCK PATENT GMBH (DE) | 2025-11-27 | — | — | WO | disclosed |
| EP-4622987-A1 | NEGATIVE NMDA-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | Sage Therapeutics, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| US-12410271-B1 | CO2 chemical reaction viscosity-increasing type polymer surfactant for gas channeling control during CO2 flooding in offshore heavy oil reservoirs, preparation method therefor and use thereof | CHINA UNIVERSITY OF PETROLEUM (EAST CHINA) (CN) | 2025-09-09 | — | — | US | disclosed |
| CN-114787160-B | Imidazopyridazine and imidazopyridine compounds as inhibitors of activin receptor-like kinase-2 | 因赛特公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-119661570-A | CO (carbon monoxide)2Lewis acid monomer for reaction adhesion-promoting type surface polymerization agent and preparation method thereof | 中国石油大学(华东) | 2025-03-21 | — | — | CN | disclosed |
| WO-1991008184-A2 | 1,2-DISUBSTITUTED 2,6-DIFLUOROBENZENE COMPOUNDS AND LIQUID CRYSTAL MEDIA | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-06-13 | — | — | WO | disclosed |
| EP-0423926-A1 | Difluorobenzonitrile derivatives | Chisso Corporation (JP) | 1991-04-24 | — | — | EP | disclosed |
| US-4424229-A | ANALGESICS | A/S DUMEX (DUMEX LTD.) (DK) | 1984-01-03 | — | — | US | disclosed |
| EP-0005219-B1 | ARYLIMIDAZOLES, THEIR SYNTHESIS AND PHARMACEUTICAL OR VETERINARY PREPARATIONS CONTAINING THEM | A/S Dumex (Dumex Ltd.) (DK) | 1981-07-22 | — | — | EP | disclosed |
| EP-0005219-A1 | Arylimidazoles, their synthesis and pharmaceutical or veterinary preparations containing them | A/S Dumex (Dumex Ltd.) (DK) | 1979-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204485-A1 | Process of preparing esters and ethers of probucol and derivatives thereof | NR3C2, MGLL, GCG | CA12 2274/4885CA1 2271/4885CA9 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.