Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.30 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472590 | 0.93 | STK17A (0.31) | STK17A | |
| SCHEMBL20219573 | 0.83 | TLR7 (0.35) | TRPM8 | |
| SCHEMBL23472112 | 0.73 | TLR7 (0.34) | TRPM8 | |
| SCHEMBL20219627 | 0.71 | TLR7 (0.44) | TRPM8 | |
| SCHEMBL20219474 | 0.69 | TLR8 (0.33) | STK17A | |
| SCHEMBL20219550 | 0.68 | CXCR2 (0.38) | TRPM8 | |
| SCHEMBL23472468 | 0.68 | TRPM8 (0.42) | TRPM8 | |
| SCHEMBL20413303 | 0.68 | TLR7 (0.37) | TRPM8 | |
| SCHEMBL13195109 | 0.67 | TLR7 (0.46) | — | |
| SCHEMBL20219539 | 0.67 | TLR7 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |