Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT1 | P54687 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27637183 | 0.78 | APOBEC3G (0.50) | BCAT1APOBEC3GHSD11B1ALDH1A1HTR2A | |
| SCHEMBL19021881 | 0.76 | APOBEC3G (0.48) | BCAT1APOBEC3GHSD11B1ALDH1A1HTR2A | |
| SCHEMBL14855030 | 0.73 | HSD11B1 (0.53) | APOBEC3GHSD11B1ALDH1A1KMT2AKDM4E | |
| SCHEMBL182738 | 0.72 | LMNA (0.67) | APOBEC3GHSD11B1ALDH1A1KMT2AKDM4E | |
| SCHEMBL26413509 | 0.72 | APOBEC3G (0.58) | APOBEC3GHSD11B1ALDH1A1HTR2AHTR2C | |
| SCHEMBL11211293 | 0.72 | APOBEC3G (0.58) | APOBEC3GHSD11B1ALDH1A1HTR2AHTR2C | |
| SCHEMBL28365619 | 0.72 | APOBEC3G (0.44) | BCAT1APOBEC3GHSD11B1ALDH1A1HTR2A | |
| SCHEMBL10954851 | 0.71 | APOBEC3G (0.52) | BCAT1APOBEC3GHSD11B1ALDH1A1HTR2A | |
| SCHEMBL4110091 | 0.71 | LMNA (0.70) | BCAT1ALDH1A1HTR2AHTR2CKMT2A | |
| SCHEMBL4972178 | 0.71 | LMNA (0.70) | BCAT1ALDH1A1HTR2AHTR2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171522-A1 | DERIVATIVES OF AN FGFR INHIBITOR | INCYTE CORPORATION | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171522-A1 | DERIVATIVES OF AN FGFR INHIBITOR | FGFR1, FGFR2, FGFR4 | BCAT1 831/4885APOBEC3G 4576/4885HSD11B1 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.