Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29843930 | 0.99 | STING1 (0.40) | STING1MEN1KMT2ASTAT1ALDH1A1 | |
| Iodide SCHEMBL2347798 | 0.84 | HDAC4 (0.36) | ALDH1A1NOTUMPOLBNPSR1GAA | |
| Iodide SCHEMBL2347792 | 0.84 | HDAC4 (0.36) | ALDH1A1NOTUMPOLBNPSR1GAA | |
| Iodide SCHEMBL1928828 | 0.83 | HTR3A (0.41) | STING1ALDH1A1TSHR | |
| SCHEMBL29843820 | 0.82 | HDAC4 (0.37) | ALDH1A1NOTUMPOLBNPSR1GAA | |
| SCHEMBL28954321 | 0.75 | MEN1 (0.42) | STING1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28283765 | 0.75 | HDAC4 (0.43) | ALDH1A1TSHRNOTUMMAPT | |
| SCHEMBL18324318 | 0.72 | CCR1 (0.46) | MEN1KMT2AALDH1A1CES2CES1 | |
| SCHEMBL28979084 | 0.65 | CASP1 (0.37) | MEN1KMT2APOLBGAA | |
| SCHEMBL28285349 | 0.64 | CSNK2A1 (0.40) | MEN1KMT2ATSHRNOTUMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11404650-B2 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2022-08-02 | — | — | US | disclosed |
| US-10381579-B2 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2019-08-13 | — | — | US | disclosed |
| US-20150249225-A1 | STABILITY OLED MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2015-09-03 | — | — | US | disclosed |
| US-9051344-B2 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2015-06-09 | — | — | US | disclosed |
| US-7902374-B2 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1878053-B1 | STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY | UNIVERSAL DISPLAY CORP (US) | 2009-08-26 | — | — | EP | disclosed |
| US-7534505-B2 | Organometallic compounds for use in electroluminescent devices | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-05-19 | — | — | US | disclosed |
| WO-2008054584-A1 | IMPROVED STABILITY OLED MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2008-05-08 | — | — | WO | disclosed |
| US-20070088167-A1 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION | 2007-04-19 | — | — | US | disclosed |
| US-20060251923-A1 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION | 2006-11-09 | — | — | US | disclosed |
| US-20050260448-A1 | Novel organometallic compounds for use in electroluminescent devices | UNIVERSAL DISPLAY CORPORATION | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11404650-B2 | Stability OLED materials and devices | OCIAD2, OCIAD1, OSBP2 | STING1 4212/4885MEN1 3298/4885KMT2A 2787/4885 |
| US-10381579-B2 | Stability OLED materials and devices | OCIAD2, OCIAD1, OSBP2 | STING1 4225/4885MEN1 3324/4885KMT2A 2798/4885 |
| US-20150249225-A1 | STABILITY OLED MATERIALS AND DEVICES | OCIAD2, OCIAD1, OSBP2 | STING1 4225/4885MEN1 3324/4885KMT2A 2798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.