Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424184 | 0.82 | ALDH1A1 (0.39) | ALDH1A1NR4A2TSHRMEN1KMT2A | |
| SCHEMBL1424319 | 0.77 | TSHR (0.40) | ALDH1A1NR4A2TSHRMEN1KMT2A | |
| SCHEMBL1424188 | 0.76 | ALDH1A1 (0.39) | ALDH1A1NR4A2TSHRMEN1KMT2A | |
| SCHEMBL1424582 | 0.73 | ALDH1A1 (0.37) | ALDH1A1NR4A2TSHRMEN1KMT2A | |
| SCHEMBL10206251 | 0.72 | NOTUM (0.34) | NR4A2TSHRMEN1KMT2ASLC6A3 | |
| SCHEMBL2342253 | 0.71 | EPAS1 (0.37) | ALDH1A1TSHRMEN1KMT2ASLC6A2 | |
| SCHEMBL6164994 | 0.70 | ALDH1A1 (0.38) | ALDH1A1NR4A2TSHRMEN1KMT2A | |
| SCHEMBL1424455 | 0.69 | MAPT (0.36) | ALDH1A1MEN1KMT2ALMNAPKM | |
| SCHEMBL9932205 | 0.69 | VCAM1 (0.41) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL2349201 | 0.67 | NPSR1 (0.47) | ALDH1A1KDM4ENOTUMLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962529-B2 | Substituted picolinic acids, salts and acid derivatives thereof, and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2015-02-24 | — | — | US | disclosed |
| US-20120157314-A1 | NOVEL SUBSTITUTED PICOLINIC ACIDS, SALTS AND ACID DERIVATIVES THEREOF, AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-21 | — | — | US | disclosed |
| EP-1498413-B1 | 4-Aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2011-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157314-A1 | NOVEL SUBSTITUTED PICOLINIC ACIDS, SALTS AND ACID DERIVATIVES THEREOF, AND USE THEREOF AS HERBICIDES | HPD, ALAD, DDT | ALDH1A1 830/4885NR4A2 2119/4885TSHR 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.