SCHEMBL2348418

SCHEMBL2348418

CCCC[Sn+2]C.C[O-].C[O-]

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.35
CES2 O00748 2/20 0.32
CES1 P23141 2/20 0.32
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11682272 0.90
Hydrochloric Acid SCHEMBL11681948 0.78 TSHR (0.50) TSHRLMNATHRBALDH1A1
SCHEMBL2474422 0.77 ALDH1A1 (0.33) TSHRALDH1A1TDP1
SCHEMBL55393 0.76 TSHR (0.40) TSHRLMNATHRBCES2CES1
Thioglycolic Acid SCHEMBL33524973 0.75 CA1 (0.43) CES2CES1
SCHEMBL2344460 0.71 TSHR (0.35) TSHRLMNATHRBCES2CES1
SCHEMBL2345932 0.71 TSHR (0.35) TSHRLMNATHRBCES2CES1
SCHEMBL8022845 0.69 NFKB1 (0.41) TSHRLMNAALDH1A1
SCHEMBL11732100 0.67
SCHEMBL8037648 0.67 DNM1 (0.35) TSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1460056-B1 METHOD FOR PRODUCING A CARBONIC ESTER ASAHI KASEI CHEMICALS CORP (JP) 2011-10-05 EP disclosed
EP-1640357-B1 METHOD FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-31 EP disclosed
US-7652122-B2 Method for producing an aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-01-26 US disclosed
US-7435842-B2 Process for producing carbonic ester ASAHI KASEI CHEMICALS CORPORATION (JP) 2008-10-14 US disclosed
US-20070055042-A1 Method for producing an aromatic carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2007-03-08 US disclosed
EP-1640357-A1 METHOD FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2006-03-29 EP disclosed
US-20050080274-A1 Process for producing carbonic ester ASAHI KASEI KABUSHIKI KAISHA (JP) 2005-04-14 US disclosed
EP-1460056-A1 PROCESS FOR PRODUCING CARBONIC ESTER Asahi Kasei Chemicals Corporation (JP) 2004-09-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080274-A1 Process for producing carbonic ester CYP2E1, ADH1A, ALKBH3 TSHR 3770/4885LMNA 4400/4885THRB 3740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.