Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.33 |
| ▸ | KDM1A | O60341 | 7/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157173 | 0.82 | ABCC1 (0.37) | CYP11B2ALDH1A1MAPK1CYP11B1MAP4K1 | |
| SCHEMBL2158167 | 0.82 | SIRT3 (0.46) | CYP11B2SIRT3TDP1CYP11B1 | |
| SCHEMBL2157447 | 0.80 | CYP11B2 (0.43) | CYP11B2ALDH1A1CYP11B1MAP4K1 | |
| SCHEMBL2157416 | 0.74 | CYP11B2 (0.41) | CYP11B2SIRT3TDP1ALDH1A1CYP11B1 | |
| SCHEMBL7946362 | 0.66 | CDC7 (0.50) | CYP11B2 | |
| SCHEMBL2158205 | 0.65 | KDM4E (0.45) | CYP11B2ALDH1A1CYP11B1PTGS2 | |
| SCHEMBL7957597 | 0.65 | HPGD (0.37) | ALDH1A1 | |
| SCHEMBL7954859 | 0.65 | MKNK1 (0.43) | ALDH1A1MAP3K14 | |
| SCHEMBL2157288 | 0.64 | MKNK1 (0.46) | CYP11B2 | |
| SCHEMBL4039386 | 0.64 | GPR119 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361253-A1 | COMPOUNDS | Selcia Limited (GB) | 2011-08-31 | — | — | EP | claimed |
| WO-2010029364-A1 | COMPOUNDS | SELCIA LIMITED (GB) | 2010-03-18 | — | — | WO | claimed |