Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 13/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953580 | 0.79 | CYP11B1 (0.37) | CYP11B2CYP11B1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7590022 | 0.78 | CYP11B2 (0.38) | CYP11B2CYP11B1SIGMAR1ALDH1A1 | |
| SCHEMBL2157932 | 0.78 | ALDH1A1 (0.40) | CYP11B2CYP11B1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL2158167 | 0.76 | SIRT3 (0.46) | CYP11B2CYP11B1 | |
| SCHEMBL2157173 | 0.74 | ABCC1 (0.37) | CYP11B2CYP11B1MAP4K1ABL1KDM4E | |
| SCHEMBL7954901 | 0.73 | CYP11B2 (0.40) | CYP11B2CYP11B1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7592203 | 0.73 | CNR2 (0.37) | CYP11B2CYP11B1KDM4EALDH1A1USP2 | |
| SCHEMBL7953649 | 0.73 | CYP11B2 (0.44) | CYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL7588929 | 0.70 | CYP11B1 (0.42) | CYP11B2CYP11B1ALDH1A1L3MBTL1 | |
| SCHEMBL17809787 | 0.68 | CYP11B2 (0.41) | CYP11B2CYP11B1MAP4K1ABL1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184011-A1 | Compounds | SELCIA LIMITED (GB) | 2011-07-28 | — | — | US | claimed |
| EP-2361253-A1 | COMPOUNDS | Selcia Limited (GB) | 2011-08-31 | — | — | EP | disclosed |
| US-20110184011-A1 | Compounds | SELCIA LIMITED (GB) | 2011-07-28 | — | — | US | disclosed |
| WO-2010029364-A1 | COMPOUNDS | SELCIA LIMITED (GB) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184011-A1 | Compounds | COL1A1, ALDH1A2, COL2A1 | CYP11B2 164/4885CYP11B1 117/4885MAP4K1 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.