Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | ILK | Q13418 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22609254 | 0.85 | DHODH (0.46) | MAPTDHODHALDH1A1HTTPIM1 | |
| SCHEMBL29552554 | 0.82 | HTR2C (0.40) | MAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL23486570 | 0.79 | ILK (0.57) | MAPTDHODHALDH1A1HPGDHSD17B10 | |
| SCHEMBL11136818 | 0.78 | FABP4 (0.45) | FABP4MAPTGFERNGLY1DHODH | |
| SCHEMBL3525990 | 0.77 | DHODH (0.56) | FABP4MAPTGFERNGLY1DHODH | |
| SCHEMBL28369905 | 0.74 | HSD17B10 (0.42) | MAPTDHODHALDH1A1KDM4EHPGD | |
| SCHEMBL4907684 | 0.71 | GRM5 (0.49) | FABP4MAPTGFERNGLY1ALDH1A1 | |
| SCHEMBL11822171 | 0.70 | KDM4E (0.43) | MAPTALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL28567393 | 0.69 | KDM4E (0.44) | MAPTALDH1A1KDM4EALOX15TSHR | |
| SCHEMBL10917448 | 0.69 | FABP4 (0.46) | FABP4MAPTGFERNGLY1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | PNPO, XDH, GLS | FABP4 4410/4885MAPT 2376/4885GFER 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.