Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | SMO | Q99835 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.54 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.52 |
| ▸ | CTRC | Q99895 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30501156 | 1.00 | MAP4K4 (0.62) | MAP4K4PIM1CYP1A2SMOCNR1 | |
| SCHEMBL18603218 | 1.00 | MAP4K4 (0.62) | MAP4K4PIM1CYP1A2SMOCNR1 | |
| SCHEMBL29854571 | 0.90 | ASIC3 (0.61) | MAP4K4PIM1SMOTGFBR1ASIC3 | |
| SCHEMBL24291931 | 0.90 | ASIC3 (0.61) | MAP4K4PIM1SMOTGFBR1ASIC3 | |
| SCHEMBL17694751 | 0.90 | ASIC3 (0.61) | MAP4K4PIM1SMOTGFBR1ASIC3 | |
| SCHEMBL29578028 | 0.88 | ASIC3 (0.63) | MAP4K4PIM1SMOTGFBR1ASIC3 | |
| SCHEMBL912763 | 0.88 | ASIC3 (0.63) | MAP4K4PIM1SMOTGFBR1ASIC3 | |
| SCHEMBL2989004 | 0.87 | CTRC (0.50) | MAP4K4PIM1CYP1A2SMOCNR1 | |
| SCHEMBL29794052 | 0.86 | ASIC3 (0.61) | MAP4K4PIM1SMOTGFBR1ASIC3 | |
| SCHEMBL27724751 | 0.86 | ASIC3 (0.61) | MAP4K4PIM1SMOTGFBR1ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230056324-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| WO-2021110720-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230056324-A1 | METAL COMPLEXES | MCU, IMMT, SOD1 | MAP4K4 4234/4885PIM1 1309/4885CYP1A2 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.