Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290744 | 0.86 | SYNJ2 (0.42) | SYNJ2SLC22A1TYMPMAOBXDH | |
| SCHEMBL23488597 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AGAASYNJ2 | |
| SCHEMBL21112979 | 0.84 | MAOB (0.45) | SMN1; SMN2SYNJ2SLC22A1ALDH1A1TYMP | |
| SCHEMBL23488254 | 0.81 | CHRNB2 (0.45) | SYNJ2TYMPMAOBXDH | |
| SCHEMBL23488247 | 0.81 | RAB9A (0.57) | SMN1; SMN2NPC1RAB9AGAASYNJ2 | |
| SCHEMBL21112930 | 0.80 | TYMP (0.43) | SYNJ2SLC22A1TYMPMAOBPOLB | |
| SCHEMBL5604917 | 0.79 | NPC1 (0.69) | SMN1; SMN2NPC1RAB9AGAAPTPN1 | |
| SCHEMBL27464799 | 0.78 | PTPN1 (0.47) | PTPN1ALDH1A1MAOBPOLBMEN1 | |
| SCHEMBL16018720 | 0.78 | LGALS3 (0.45) | SYNJ2PTPN1ALDH1A1HTTTYMP | |
| SCHEMBL19613824 | 0.76 | PTPN1 (0.44) | PTPN1ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | SMN1; SMN2 3945/4885NPC1 1840/4885RAB9A 1043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.