Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15162261 | 0.79 | HSP90AA1 (0.54) | L3MBTL1ADORA2BLMNAALDH1A1PKM | |
| SCHEMBL16296963 | 0.79 | ALDH1A1 (0.72) | L3MBTL1ADORA2BLMNAALDH1A1PKM | |
| SCHEMBL1126706 | 0.78 | ALDH1A1 (0.62) | LMNAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL16240397 | 0.75 | MAPK1 (0.70) | L3MBTL1LMNAALDH1A1MAPK1POLB | |
| SCHEMBL6469660 | 0.75 | LMNA (0.60) | L3MBTL1ADORA2BLMNAALDH1A1PKM | |
| SCHEMBL26597141 | 0.74 | RAB9A (0.61) | L3MBTL1LMNAALDH1A1MAPK1HPGD | |
| SCHEMBL1991859 | 0.74 | ALDH1A1 (0.53) | LMNAALDH1A1MAPK1POLBHPGD | |
| SCHEMBL24584761 | 0.73 | NPC1 (0.63) | LMNAALDH1A1MAPK1POLBHPGD | |
| SCHEMBL23488197 | 0.73 | L3MBTL1 (0.61) | L3MBTL1ADORA2BALDH1A1PKMPOLB | |
| SCHEMBL24584793 | 0.73 | ALDH1A1 (0.56) | LMNAALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110010-A1 | NOVEL PYRROLE COMPOUND | 微境生物医药科技(上海)有限公司 | 2021-06-10 | — | — | WO | disclosed |