Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486304 | 0.87 | MAPT (0.56) | PARP10SMN1; SMN2MAPTTSHRCYP2C19 | |
| SCHEMBL23488402 | 0.85 | F7 (0.63) | NNMTSMN1; SMN2MAPTTSHRCYP2C19 | |
| SCHEMBL22557648 | 0.82 | KMT2A (0.47) | PARP10SMN1; SMN2GRM5MAPTPOLB | |
| SCHEMBL31426894 | 0.80 | KMT2A (0.53) | PARP10SMN1; SMN2GRM5MAPTHSD17B10 | |
| SCHEMBL27633082 | 0.79 | KMT2A (0.51) | SMN1; SMN2MAPTTSHRHSD17B10L3MBTL1 | |
| SCHEMBL20599489 | 0.79 | MAPT (0.47) | PARP10SMN1; SMN2SLC6A3GRM5MAPT | |
| SCHEMBL1245960 | 0.79 | OPRM1 (0.71) | NNMTPARP10OPRM1OPRK1OPRD1 | |
| SCHEMBL27653513 | 0.79 | ALDH1A1 (0.65) | SMN1; SMN2SLC6A3GRM5MAPTTSHR | |
| Hydrochloric Acid SCHEMBL5010396 | 0.77 | OPRM1 (0.69) | NNMTPARP10OPRM1OPRK1OPRD1 | |
| SCHEMBL23488259 | 0.76 | PARP10 (0.62) | NNMTPARP10OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | NNMT 4462/4885PARP10 1135/4885OPRM1 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.