SCHEMBL2348901

SCHEMBL2348901

CS(=O)(=O)c1ccc(N)nn1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.33
PIP5K1C O60331 1/20 0.33
PIK3CB P42338 1/20 0.33
PI4KA P42356 1/20 0.33
PIK3CG P48736 1/20 0.33
PI4KB Q9UBF8 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
CA14 Q9ULX7 1/20 0.33
GLP1R P43220 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 1/20 0.32
BCAT2 O15382 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3603956 0.74 MEN1 (0.30)
SCHEMBL3603960 0.73 ENPP2 (0.38)
SCHEMBL30252450 0.73 GAA (0.38) GLP1RKDM4E
SCHEMBL16430495 0.73 EDNRA (0.32)
SCHEMBL3303195 0.73
SCHEMBL427846 0.73 GAA (0.38) GLP1RKDM4E
Hydrochloric Acid SCHEMBL5203709 0.71 GAA (0.44) CA12CA1CA2CA9L3MBTL1
SCHEMBL31490392 0.71
SCHEMBL1255843 0.71
SCHEMBL12920693 0.70 ALDH1A1 (0.36) CA12CA1CA2CA6CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110183434-B Oxadiazole compound and preparation method and application thereof 南京林业大学 2022-07-12 CN disclosed
EP-3638669-A1 SUBSTITUTED PYRROLOPYRIDINE-DERIVATIVES Bayer Pharma Aktiengesellschaft (DE) 2020-04-22 EP disclosed
WO-2018228920-A1 SUBSTITUTED PYRROLOPYRIDINE-DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-12-20 WO disclosed
EP-1932835-B1 METHOD FOR PRODUCING 2,3-DIHYDROPYRIDAZINE COMPOUND SUMITOMO CHEMICAL CO (JP) 2013-12-25 EP disclosed
US-8008485-B2 Process for producing 2,3-dihydropyridazine compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-30 US disclosed
US-20090105475-A1 PROCESS FOR PRODUCING 2,3-DIHYDROPYRIDAZINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-23 US disclosed
EP-1932835-A1 METHOD FOR PRODUCING 2,3-DIHYDROPYRIDAZINE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105475-A1 PROCESS FOR PRODUCING 2,3-DIHYDROPYRIDAZINE COMPOUND DDC, DHPS, QDPR PIK3CD 3652/4885PIP5K1C 1143/4885PIK3CB 3210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.