Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPY4R | P50391 | 4/20 | 0.31 |
| ▸ | NPY1R | P25929 | 3/20 | 0.31 |
| ▸ | NPY2R | P49146 | 3/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13254058 | 1.00 | ITGB3 (0.34) | ITGB3ITGA2BALOX15MEN1CYP1A2 | |
| SCHEMBL24932573 | 0.91 | CHRNB2 (0.30) | — | |
| SCHEMBL23988965 | 0.80 | NPY4R (0.36) | ITGB3ITGA2BALOX15MEN1CYP1A2 | |
| SCHEMBL24529722 | 0.80 | MEN1 (0.36) | ITGB3ITGA2BALOX15MEN1CYP1A2 | |
| SCHEMBL20104610 | 0.80 | MEN1 (0.36) | ITGB3ITGA2BALOX15MEN1CYP1A2 | |
| SCHEMBL26894997 | 0.79 | ALOX15 (0.31) | ALOX15MEN1CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL20104600 | 0.78 | MEN1 (0.35) | ITGB3ITGA2BALOX15MEN1CYP1A2 | |
| SCHEMBL13254057 | 0.78 | CPB2 (0.35) | — | |
| SCHEMBL21941031 | 0.77 | MEN1 (0.34) | ALOX15MEN1CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL19729232 | 0.77 | ALDH1A1 (0.32) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113524-A2 | GLP2 RECEPTOR AGONISTS AND METHODS OF USE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-06-10 | — | — | WO | disclosed |