Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19211242 | 0.94 | CA2 (0.40) | CA2TLR9MEN1KMT2AKDM4E | |
| SCHEMBL19249247 | 0.91 | MMP13 (0.47) | TLR9MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL19248874 | 0.90 | EGLN2 (0.42) | HDAC1BCHECNR2TLR9MEN1 | |
| SCHEMBL19248873 | 0.88 | NQO2 (0.45) | HDAC1MEN1KMT2AKDM4ASYK | |
| SCHEMBL20729415 | 0.87 | BCHE (0.43) | HDAC1BCHECNR2TLR9MEN1 | |
| SCHEMBL19249244 | 0.87 | CA2 (0.40) | CA2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL23491566 | 0.83 | ALOX5 (0.38) | HDAC1CA2TLR9MEN1KMT2A | |
| SCHEMBL19248870 | 0.79 | EGLN2 (0.40) | HPGDKDM4A | |
| SCHEMBL19211238 | 0.78 | PLA2G2A (0.52) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL20729327 | 0.78 | CYP2C9 (0.37) | BCHECNR2CA2TLR9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414229-B1 | QUINOLINONE LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2021-06-16 | — | — | EP | disclosed |