Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13160476 | 0.84 | THRB (0.66) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL28353967 | 0.82 | THRB (0.60) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL14665703 | 0.79 | THRB (0.65) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL15277473 | 0.79 | THRB (0.65) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL16327 | 0.76 | TSHR (0.56) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL16939126 | 0.76 | TSHR (0.60) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL4361549 | 0.76 | TSHR (0.56) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL5053935 | 0.75 | TSHR (0.54) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL8861475 | 0.75 | TSHR (0.54) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL8861451 | 0.75 | TSHR (0.54) | THRBTSHRHPGDALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11246848-B2 | Three-dimensional cage-like hyperbranched monomer, and preparation method and application thereof | YANGTZE UNIVERSITY (CN) | 2022-02-15 | — | — | US | disclosed |
| US-20210177791-A1 | THREE-DIMENSIONAL CAGE-LIKE HYPERBRANCHED MONOMER, AND PREPARATION METHOD AND APPLICATION THEREOF | YANGTZE UNIVERSITY (CN) | 2021-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11246848-B2 | Three-dimensional cage-like hyperbranched monomer, and preparation method and application thereof | YWHAH, YWHAB, YAP1 | THRB 3418/4885TSHR 3863/4885HPGD 1282/4885 |
| US-20210177791-A1 | THREE-DIMENSIONAL CAGE-LIKE HYPERBRANCHED MONOMER, AND PREPARATION METHOD AND APPLICATION THEREOF | YWHAH, HDHD5, YWHAB | THRB 3517/4885TSHR 3827/4885HPGD 924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.